Human artificial chromosomes that bypass centromeric DNA

Glennis A. Logsdon, Craig W. Gambogi, Mikhail A. Liskovykh, Evelyne J. Barrey, Vladimir Larionov, Karen H. Miga, Patrick Heun, Ben E. Black*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Development of human artificial chromosomes that bypass centromeric DNA removes a key barrier limiting mammalian synthetic genome efforts.

Original languageEnglish
Pages (from-to)624-639
JournalCell
Volume178
Issue number3
Early online date25 Jul 2019
DOIs
Publication statusE-pub ahead of print - 25 Jul 2019

Keywords / Materials (for Non-textual outputs)

  • centromere
  • chromatin
  • epigenetics
  • HAC
  • histone
  • human artificial chromosome
  • kinetochore
  • mitosis
  • nucleosome
  • synthetic chromosome

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