Original language | English |
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Journal | Cell Stem Cell |
DOIs | |
Publication status | Published - 3 Mar 2022 |
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Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease. / Hallett, John; Ferreira-Gonzalez, Sofía; Man, Janet; Kilpatrick, Alastair; Esser, Hannah; Thirwell, Kayleigh; Macmillan, Mark; Rodrigo Torres, Daniel; Dwyer, Benjamin; Gadd, Victoria; Ashmore-Harris, Candice; Lu, Wei-Yu; Thomson, John; Jansen, Maurits; O'Duibhir, Eoghan; Starkey Lewis, Philip; Campana, Lara; Aird, Rhona; Bate, Thomas; Fraser, Alasdair R; Campbell, John D M; Oniscu, Gabriel C; Hay, David C; Callanan, Anthony; Forbes, Stuart J.
In: Cell Stem Cell, 03.03.2022.Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease
AU - Hallett, John
AU - Ferreira-Gonzalez, Sofía
AU - Man, Janet
AU - Kilpatrick, Alastair
AU - Esser, Hannah
AU - Thirwell, Kayleigh
AU - Macmillan, Mark
AU - Rodrigo Torres, Daniel
AU - Dwyer, Benjamin
AU - Gadd, Victoria
AU - Ashmore-Harris, Candice
AU - Lu, Wei-Yu
AU - Thomson, John
AU - Jansen, Maurits
AU - O'Duibhir, Eoghan
AU - Starkey Lewis, Philip
AU - Campana, Lara
AU - Aird, Rhona
AU - Bate, Thomas
AU - Fraser, Alasdair R
AU - Campbell, John D M
AU - Oniscu, Gabriel C
AU - Hay, David C
AU - Callanan, Anthony
AU - Forbes, Stuart J
N1 - Funding Information: This work was supported by the UK Medical Research Council. S.F.-G. T.Y.M. and K.T. were funded by Developmental Pathway Funding MRC, MR/P016839/1. J.M.H. was funded by the Edinburgh Clinical Academic Track Cancer Research UK PhD fellowship and the Edinburgh and Lothians Health Foundation Liver Transplant Fund. This work has made use of the resources provided by the Edinburgh Compute and Data Facility (ECDF). Conceptualization and design, J.M.H. S.F.-G. W.Y.-L. and S.J.F.; data generation, J.M.H. S.F.-G. T.Y.M. A.M.K. H.E. K.T. M.T.M. D.R.-T. B.J.D. V.L.G. C.A.-H. W.Y.-L. J.P.T. M.A.J. E.O. P.J.S.L. L.C. R.E.A. T.S.R.B. A.R.F. J.D.M.C. G.C.O. D.C.H. and A.C.; data analysis and interpretation, J.M.H. S.F.-G. B.J.D. K.T. J.P.T. A.M.K. W.Y.-L. E.O. M.A.J. D.R.-T. P.J.S.L. L.C. A.R.F. J.D.M.C. D.C.H. G.C.O. and S.J.F.; manuscript preparation, S.F.-.G.; writing – review & editing, S.F.-G. D.R.-T. A.M.K. and S.J.F.; funding acquisition, S.J.F. S.J.F. and J.D.M.C. are founders and scientific advisors of Resolution Therapeutics Ltd (not related to this study). D.C.H. is a founder, director, and shareholder at Stemnovate Limited and Stimuliver ApS (not related to this study). We worked to ensure gender balance in the recruitment of human subjects. We worked to ensure sex balance in the selection of non-human subjects. One or more of the authors of this paper self-identifies as a member of the LGBTQ+ community. One or more of the authors of this paper self-identifies as living with a disability. Funding Information: This work was supported by the UK Medical Research Council . S.F.-G., T.Y.M., and K.T. were funded by Developmental Pathway Funding MRC , MR/P016839/1 . J.M.H. was funded by the Edinburgh Clinical Academic Track Cancer Research UK PhD fellowship and the Edinburgh and Lothians Health Foundation Liver Transplant Fund . This work has made use of the resources provided by the Edinburgh Compute and Data Facility (ECDF). Publisher Copyright: © 2022 The Authors
PY - 2022/3/3
Y1 - 2022/3/3
U2 - 10.1016/j.stem.2022.02.006
DO - 10.1016/j.stem.2022.02.006
M3 - Article
JO - Cell Stem Cell
JF - Cell Stem Cell
SN - 1934-5909
ER -