Human Leydig cells are productively infected by some HIV-2 and SIV strains but not by HIV-1

Samantha Willey; Vanessa Roulet; Jacqueline D Reeves; Marie-Laure Kergadallan; Elaine Thomas; Aine McKnight; Bernard Jégou; Nathalie Dejucq-Rainsford

doi:10.1097/01.aids.0000042968.95433.66

Human Leydig cells are productively infected by some HIV-2 and SIV strains but not by HIV-1

Samantha Willey, Vanessa Roulet, Jacqueline D Reeves, Marie-Laure Kergadallan, Elaine Thomas, Aine McKnight, Bernard Jégou, Nathalie Dejucq-Rainsford

Deanery of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

With the use of highly active antiretroviral therapy, the identification of HIV reservoirs within the body has become an important issue. However, the testis has been largely ignored despite representing a pharmacologic sanctuary which could act as a viral reservoir.

Original language	English
Pages (from-to)	183-8
Number of pages	6
Journal	AIDS
Volume	17
Issue number	2
DOIs	https://doi.org/10.1097/01.aids.0000042968.95433.66
Publication status	Published - 24 Jan 2003

Keywords

CD4-Positive T-Lymphocytes
Cells, Cultured
Disease Susceptibility
HIV Infections
HIV-1
HIV-2
Humans
Leydig Cells
Male
Receptors, HIV
Receptors, Virus
Simian Acquired Immunodeficiency Syndrome
Simian immunodeficiency virus

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10.1097/01.aids.0000042968.95433.66

Cite this

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title = "Human Leydig cells are productively infected by some HIV-2 and SIV strains but not by HIV-1",

abstract = "With the use of highly active antiretroviral therapy, the identification of HIV reservoirs within the body has become an important issue. However, the testis has been largely ignored despite representing a pharmacologic sanctuary which could act as a viral reservoir.",

keywords = "CD4-Positive T-Lymphocytes, Cells, Cultured, Disease Susceptibility, HIV Infections, HIV-1, HIV-2, Humans, Leydig Cells, Male, Receptors, HIV, Receptors, Virus, Simian Acquired Immunodeficiency Syndrome, Simian immunodeficiency virus",

author = "Samantha Willey and Vanessa Roulet and Reeves, {Jacqueline D} and Marie-Laure Kergadallan and Elaine Thomas and Aine McKnight and Bernard J{\'e}gou and Nathalie Dejucq-Rainsford",

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T1 - Human Leydig cells are productively infected by some HIV-2 and SIV strains but not by HIV-1

AU - Willey, Samantha

AU - Roulet, Vanessa

AU - Reeves, Jacqueline D

AU - Kergadallan, Marie-Laure

AU - Thomas, Elaine

AU - McKnight, Aine

AU - Jégou, Bernard

AU - Dejucq-Rainsford, Nathalie

PY - 2003/1/24

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KW - CD4-Positive T-Lymphocytes

KW - Cells, Cultured

KW - Disease Susceptibility

KW - HIV Infections

KW - HIV-1

KW - HIV-2

KW - Humans

KW - Leydig Cells

KW - Male

KW - Receptors, HIV

KW - Receptors, Virus

KW - Simian Acquired Immunodeficiency Syndrome

KW - Simian immunodeficiency virus

U2 - 10.1097/01.aids.0000042968.95433.66

DO - 10.1097/01.aids.0000042968.95433.66

M3 - Article

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JO - AIDS

JF - AIDS

SN - 0269-9370

IS - 2

ER -

Human Leydig cells are productively infected by some HIV-2 and SIV strains but not by HIV-1

Abstract

Keywords

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