HYPE applied to the modelling of hybrid biological systems

Vashti Galpin, Jane Hillston, Luca Bortolussi

Research output: Contribution to journalArticlepeer-review


HYPE is a process algebra developed to model hybrid systems – systems that show both continuous and discrete behaviour. It is novel because it allows for the modelling of individual flows which means that subcomponents can be modelled in terms of these flows and do not need to be described monolithically. Biological systems display discrete behaviour inherently, but modellers may choose to model systems in a hybrid fashion, often to deal with differences in scale. We demonstrate how HYPE can be used to model the Repressilator.
Original languageEnglish
Pages (from-to)33-51
Number of pages19
JournalElectronic Notes in Theoretical Computer Science
Publication statusPublished - 2008


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