Identification of a pegivirus (GBV-like virus) that infects horses

Amit Kapoor, Peter Simmonds, John M Cullen, Troels Scheel, Jan L Medina, Federico Giannitti, Eiko Nishiuchi, Kenny V Brock, Peter D Burbelo, Charles M Rice, W Ian Lipkin

Research output: Contribution to journalArticlepeer-review

Abstract

Recent identification of non-primate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GBV-like viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named Equine Pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.
Original languageEnglish
Pages (from-to)7185-7190
JournalJournal of Virology
Volume87
Issue number12
Early online date17 Apr 2013
DOIs
Publication statusPublished - 17 Apr 2013

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