Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

Helen Creedon; Laura Gomez-cuadrado; Zygimante  Tarnauskaite; J. Balla; Marta Canel; Kenneth Macleod; Bryan Serrels; Craig Fraser; Asier Unciti-Broceta; Natasha Tracey; Thierry Le Bihan; Teresa Klinowska; Andrew Sims; Adam Byron; Valerie Brunton

doi:10.18632/oncotarget.7317

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

Helen Creedon, Laura Gomez-cuadrado, Zygimante Tarnauskaite, J. Balla, Marta Canel, Kenneth Macleod, Bryan Serrels, Craig Fraser, Asier Unciti-Broceta, Natasha Tracey, Thierry Le Bihan, Teresa Klinowska, Andrew Sims, Adam Byron, Valerie Brunton

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	11539-52
Journal	Oncotarget
Volume	7
Issue number	10
DOIs	https://doi.org/10.18632/oncotarget.7317
Publication status	Published - 11 Feb 2016

Keywords

RESISTANCE
BREAST CANCER
EMT
HER2
PROTEOMICS

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10.18632/oncotarget.7317Licence: Creative Commons: Attribution (CC-BY)

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapyAccepted author manuscript, 4.16 MBLicence: Creative Commons: Attribution (CC-BY)

http://www.oncotarget.com/abstract/7317Licence: Creative Commons: Attribution (CC-BY)

Invasion and metastasis; understanding and targeting an adhesion protein network - Programme Grant Renewal
Frame, M.
UK-based charities
1/05/13 → 31/08/18
Project: Research
ECRC CENTRE AWARD - STUDENTSHIP AWARD
Savill, J., Cameron, D. & Frame, M.
UK-based charities
1/01/11 → 31/10/14
Project: Research
SynthSys; formerly CSBE: Centre for Systems Biology at Edinburgh
Millar, A., Beggs, J., Ghazal, P., Goryanin, I., Hillston, J., Plotkin, G., Tollervey, D., Walton, A. & Robertson, K.
BBSRC
8/01/07 → 31/12/12
Project: Research

Cite this

Creedon, H., Gomez-cuadrado, L., Tarnauskaite, Z., Balla, J., Canel, M., Macleod, K., Serrels, B., Fraser, C., Unciti-Broceta, A., Tracey, N., Le Bihan, T., Klinowska, T., Sims, A., Byron, A., & Brunton, V. (2016). Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy. Oncotarget, 7(10), 11539-52. https://doi.org/10.18632/oncotarget.7317

@article{c8e6416d9d1c4754819b47190bbc590a,

title = "Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy",

keywords = "RESISTANCE, BREAST CANCER, EMT, HER2, PROTEOMICS",

author = "Helen Creedon and Laura Gomez-cuadrado and Zygimante Tarnauskaite and J. Balla and Marta Canel and Kenneth Macleod and Bryan Serrels and Craig Fraser and Asier Unciti-Broceta and Natasha Tracey and {Le Bihan}, Thierry and Teresa Klinowska and Andrew Sims and Adam Byron and Valerie Brunton",

note = "This work was supported by Cancer Research UK grants (C157/A15703 and C6088/A12063). The mass spectrometer was funded by a Wellcome Trust Institutional Strategic Support Fund award and a Wellcome Trust Strategic Award to the University of Edinburgh Centre for Immunity, Infection and Evolution. SynthSys is a Centre for Integrative Systems Biology funded by the Biotechnology and Biological Sciences Research Council and Engineering and Physical Sciences Research Council (reference BB/D019621/1).",

year = "2016",

month = feb,

day = "11",

doi = "10.18632/oncotarget.7317",

language = "English",

volume = "7",

pages = "11539--52",

journal = "Oncotarget",

issn = "1949-2553",

publisher = "Impact Journals",

number = "10",

}

Creedon, H, Gomez-cuadrado, L, Tarnauskaite, Z, Balla, J, Canel, M, Macleod, K, Serrels, B, Fraser, C, Unciti-Broceta, A, Tracey, N, Le Bihan, T, Klinowska, T, Sims, A, Byron, A & Brunton, V 2016, 'Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy', Oncotarget, vol. 7, no. 10, pp. 11539-52. https://doi.org/10.18632/oncotarget.7317

TY - JOUR

T1 - Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

AU - Creedon, Helen

AU - Gomez-cuadrado, Laura

AU - Tarnauskaite, Zygimante

AU - Balla, J.

AU - Canel, Marta

AU - Macleod, Kenneth

AU - Serrels, Bryan

AU - Fraser, Craig

AU - Unciti-Broceta, Asier

AU - Tracey, Natasha

AU - Le Bihan, Thierry

AU - Klinowska, Teresa

AU - Sims, Andrew

AU - Byron, Adam

AU - Brunton, Valerie

N1 - This work was supported by Cancer Research UK grants (C157/A15703 and C6088/A12063). The mass spectrometer was funded by a Wellcome Trust Institutional Strategic Support Fund award and a Wellcome Trust Strategic Award to the University of Edinburgh Centre for Immunity, Infection and Evolution. SynthSys is a Centre for Integrative Systems Biology funded by the Biotechnology and Biological Sciences Research Council and Engineering and Physical Sciences Research Council (reference BB/D019621/1).

PY - 2016/2/11

Y1 - 2016/2/11

KW - RESISTANCE

KW - BREAST CANCER

KW - EMT

KW - HER2

KW - PROTEOMICS

U2 - 10.18632/oncotarget.7317

DO - 10.18632/oncotarget.7317

M3 - Article

VL - 7

SP - 11539

EP - 11552

JO - Oncotarget

JF - Oncotarget

SN - 1949-2553

IS - 10

ER -

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

Keywords

Access to Document

Projects

Invasion and metastasis; understanding and targeting an adhesion protein network - Programme Grant Renewal

ECRC CENTRE AWARD - STUDENTSHIP AWARD

SynthSys; formerly CSBE: Centre for Systems Biology at Edinburgh

Cite this