IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies

Nancy L. Pedersen; Kaare Christensen; Anna K. Dahl; Deborah Finkel; Carol E. Franz; Margaret Gatz; Briana N. Horwitz; Boo Johansson; Wendy Johnson; William S. Kremen; Michael J. Lyons; Bo Malmberg; Matt McGue; Jenae M. Neiderhiser; Inge Petersen; Chandra A. Reynolds

doi:10.1017/thg.2012.110

IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies

Nancy L. Pedersen^*, Kaare Christensen, Anna K. Dahl, Deborah Finkel, Carol E. Franz, Margaret Gatz, Briana N. Horwitz, Boo Johansson, Wendy Johnson, William S. Kremen, Michael J. Lyons, Bo Malmberg, Matt McGue, Jenae M. Neiderhiser, Inge Petersen, Chandra A. Reynolds

^*Corresponding author for this work

School of Philosophy, Psychology and Language Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from over 17,500 participants aged 25-102 at baseline (including nearly 2,600 monogygotic and 4,300 dizygotic twin pairs and over 1,700 family members) aims to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.

Original language	English
Pages (from-to)	481-489
Number of pages	9
Journal	Twin Research and Human Genetics
Volume	16
Issue number	1
DOIs	https://doi.org/10.1017/thg.2012.110
Publication status	Published - Feb 2013

Keywords / Materials (for Non-textual outputs)

twins
gene-environment interaction
aging
longitudinal
PHYSICAL HEALTH
DANISH TWINS
COGNITIVE-ABILITIES
DEPRESSIVE SYMPTOMS
SEX-DIFFERENCES
LONELINESS
OLDER
AGE
BEHAVIOR
GENDER

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10.1017/thg.2012.110

PEDERSEN NL_ IGEMS The Consortium on Interplay of Genes and Environment Across Multiple Studies
©Pedersen, N. L., Christensen, K., Dahl, A. K., Finkel, D., Franz, C. E., Gatz, M., Horwitz, B. N., Johansson, B., Johnson, W., Kremen, W. S., Lyons, M. J., Malmberg, B., McGue, M., Neiderhiser, J. M., Petersen, I., & Reynolds, C. A. (2013). IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies. Twin Research and Human Genetics, 16(1), 481-489doi: 10.1017/thg.2012.110
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http://journals.cambridge.org/download.php?file=%2FTHG%2FTHG16_01%2FS1832427412001107a.pdf&code=4c57dfe5a7d824610e7fa9d615b280fd

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Pedersen, N. L., Christensen, K., Dahl, A. K., Finkel, D., Franz, C. E., Gatz, M., Horwitz, B. N., Johansson, B., Johnson, W., Kremen, W. S., Lyons, M. J., Malmberg, B., McGue, M., Neiderhiser, J. M., Petersen, I., & Reynolds, C. A. (2013). IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies. Twin Research and Human Genetics, 16(1), 481-489. https://doi.org/10.1017/thg.2012.110

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title = "IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies",

abstract = "The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from over 17,500 participants aged 25-102 at baseline (including nearly 2,600 monogygotic and 4,300 dizygotic twin pairs and over 1,700 family members) aims to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.",

keywords = "twins, gene-environment interaction, aging, longitudinal, PHYSICAL HEALTH, DANISH TWINS, COGNITIVE-ABILITIES, DEPRESSIVE SYMPTOMS, SEX-DIFFERENCES, LONELINESS, OLDER, AGE, BEHAVIOR, GENDER",

author = "Pedersen, {Nancy L.} and Kaare Christensen and Dahl, {Anna K.} and Deborah Finkel and Franz, {Carol E.} and Margaret Gatz and Horwitz, {Briana N.} and Boo Johansson and Wendy Johnson and Kremen, {William S.} and Lyons, {Michael J.} and Bo Malmberg and Matt McGue and Neiderhiser, {Jenae M.} and Inge Petersen and Reynolds, {Chandra A.}",

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doi = "10.1017/thg.2012.110",

language = "English",

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Pedersen, NL, Christensen, K, Dahl, AK, Finkel, D, Franz, CE, Gatz, M, Horwitz, BN, Johansson, B, Johnson, W, Kremen, WS, Lyons, MJ, Malmberg, B, McGue, M, Neiderhiser, JM, Petersen, I & Reynolds, CA 2013, 'IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies', Twin Research and Human Genetics, vol. 16, no. 1, pp. 481-489. https://doi.org/10.1017/thg.2012.110

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AU - Pedersen, Nancy L.

AU - Christensen, Kaare

AU - Dahl, Anna K.

AU - Finkel, Deborah

AU - Franz, Carol E.

AU - Gatz, Margaret

AU - Horwitz, Briana N.

AU - Johansson, Boo

AU - Johnson, Wendy

AU - Kremen, William S.

AU - Lyons, Michael J.

AU - Malmberg, Bo

AU - McGue, Matt

AU - Neiderhiser, Jenae M.

AU - Petersen, Inge

AU - Reynolds, Chandra A.

PY - 2013/2

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AB - The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from over 17,500 participants aged 25-102 at baseline (including nearly 2,600 monogygotic and 4,300 dizygotic twin pairs and over 1,700 family members) aims to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.

KW - twins

KW - gene-environment interaction

KW - aging

KW - longitudinal

KW - PHYSICAL HEALTH

KW - DANISH TWINS

KW - COGNITIVE-ABILITIES

KW - DEPRESSIVE SYMPTOMS

KW - SEX-DIFFERENCES

KW - LONELINESS

KW - OLDER

KW - AGE

KW - BEHAVIOR

KW - GENDER

U2 - 10.1017/thg.2012.110

DO - 10.1017/thg.2012.110

M3 - Article

SN - 1832-4274

VL - 16

SP - 481

EP - 489

JO - Twin Research and Human Genetics

JF - Twin Research and Human Genetics

IS - 1

ER -

IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies

Abstract

Keywords / Materials (for Non-textual outputs)

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