Image Quality With Single-Heartbeat 320-Multidetector Computed Tomographic Coronary Angiography

Michelle Claire Williams*, Nicholas W. Weir, Saeed Mirsadraee, Anne E. Scott, Neal G. Uren, Graham McKillop, Edwin J. R. van Beek, John H. Reid, David E. Newby

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Objective: We aimed to establish the feasibility of single-heartbeat 320-multidetector computed tomographic coronary angiography (CTCA) and assess variables affecting image quality.

Methods: Consecutive patients (n = 249, 38% male) underwent CTCA. Two observers assessed image quality using a 4-point scale (1, excellent; 4, poor).

Results: Mean heart rate was 60 beats per minute (95% confidence interval, 59-62); body mass index, 29 kg/m(2) (28-30); and dose-length product, 283 (266-301). During scanning, 133 (51%) received sublingual glyceryl trinitrate (GTN), 9 (4%) had ectopics, and 12 (5%) had atrial fibrillation. Diagnostic image quality was obtained in 99% with mean image quality of 1.4 (1.3, 1.5). Age, sex, atrial fibrillation, ectopics, diabetes mellitus (12%), and obstructive disease were not related to image quality. A lower heart rate and GTN were associated with improved image quality (P

Conclusions: Optimal image quality in single-heartbeat 320-multidetector CTCA is achievable in 99% of unselected patients. Image quality is improved by lower heart rate and GTN.

Original languageEnglish
Pages (from-to)444-450
Number of pages7
JournalJournal of computer assisted tomography
Issue number3
Publication statusPublished - 2014

Keywords / Materials (for Non-textual outputs)

  • computed tomographic coronary angiography
  • coronary heart disease
  • image quality
  • radiation dose
  • 320 multidetector
  • 320-MDCT


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