Imaging Cardiovascular Calcification Activity with 18F-Fluoride PET

Evangelos Tzolos; Marc R Dweck

doi:10.1007/978-3-030-46725-8_19

Imaging Cardiovascular Calcification Activity with 18F-Fluoride PET

Evangelos Tzolos, Marc R Dweck

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Abstract

Calcification is one of the body’s primary responses to injury and a key pathological feature of cardiovascular disease. Calcification activity can now be imaged using 18F-fluoride PET/CT or MR/PET, providing different information compared to established macroscopic calcification imaged with computed tomography. Indeed 18F-fluoride PET has now been explored in a wide range of conditions including aortic stenosis, coronary and carotid atherosclerosis, peripheral vascular disease, aortic aneurysm disease, erectile dysfunction, and bioprosthetic valve disease, offering a marker of vascular injury and disease activity in each condition studied. We will here review the current literature investigating 18F-fluoride PET in cardiovascular disease and discuss how this novel imaging approach might advance our pathophysiological understanding and ultimately improve patient care.

Original language	English
Title of host publication	Cardiovascular Calcification and Bone Mineralization
Publisher	SpringerLink
Pages	423
Number of pages	440
DOIs	https://doi.org/10.1007/978-3-030-46725-8_19
Publication status	Published - 2 Jul 2020

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10.1007/978-3-030-46725-8_19

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title = "Imaging Cardiovascular Calcification Activity with 18F-Fluoride PET",

abstract = "Calcification is one of the body{\textquoteright}s primary responses to injury and a key pathological feature of cardiovascular disease. Calcification activity can now be imaged using 18F-fluoride PET/CT or MR/PET, providing different information compared to established macroscopic calcification imaged with computed tomography. Indeed 18F-fluoride PET has now been explored in a wide range of conditions including aortic stenosis, coronary and carotid atherosclerosis, peripheral vascular disease, aortic aneurysm disease, erectile dysfunction, and bioprosthetic valve disease, offering a marker of vascular injury and disease activity in each condition studied. We will here review the current literature investigating 18F-fluoride PET in cardiovascular disease and discuss how this novel imaging approach might advance our pathophysiological understanding and ultimately improve patient care.",

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N2 - Calcification is one of the body’s primary responses to injury and a key pathological feature of cardiovascular disease. Calcification activity can now be imaged using 18F-fluoride PET/CT or MR/PET, providing different information compared to established macroscopic calcification imaged with computed tomography. Indeed 18F-fluoride PET has now been explored in a wide range of conditions including aortic stenosis, coronary and carotid atherosclerosis, peripheral vascular disease, aortic aneurysm disease, erectile dysfunction, and bioprosthetic valve disease, offering a marker of vascular injury and disease activity in each condition studied. We will here review the current literature investigating 18F-fluoride PET in cardiovascular disease and discuss how this novel imaging approach might advance our pathophysiological understanding and ultimately improve patient care.

AB - Calcification is one of the body’s primary responses to injury and a key pathological feature of cardiovascular disease. Calcification activity can now be imaged using 18F-fluoride PET/CT or MR/PET, providing different information compared to established macroscopic calcification imaged with computed tomography. Indeed 18F-fluoride PET has now been explored in a wide range of conditions including aortic stenosis, coronary and carotid atherosclerosis, peripheral vascular disease, aortic aneurysm disease, erectile dysfunction, and bioprosthetic valve disease, offering a marker of vascular injury and disease activity in each condition studied. We will here review the current literature investigating 18F-fluoride PET in cardiovascular disease and discuss how this novel imaging approach might advance our pathophysiological understanding and ultimately improve patient care.

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M3 - Chapter (peer-reviewed)

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BT - Cardiovascular Calcification and Bone Mineralization

PB - SpringerLink

ER -

Imaging Cardiovascular Calcification Activity with 18F-Fluoride PET

Abstract

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