Imaging of cardiovascular risk in patients with Turner's syndrome

A Marin; J R Weir-McCall; D J Webb; E J R van Beek; S Mirsadraee

doi:10.1016/j.crad.2015.03.009

Imaging of cardiovascular risk in patients with Turner's syndrome

A Marin, J R Weir-McCall, D J Webb, E J R van Beek, S Mirsadraee

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Turner's syndrome is a disorder defined by an absent or structurally abnormal second X chromosome and affects around 1 in 2000 newborn females. The standardised mortality ratio in Turner's syndrome is around three-times higher than in the general female population, mainly as a result of cardiovascular disorders. Most striking is the early age at which Turner's syndrome patients develop the life-threatening complications of cardiovascular disorders compared to the general population. The cardiovascular risk stratification in Turner's syndrome is challenging and imaging is not systematically used. The aim of this article is to review cardiovascular risks in this group of patients and discuss a systematic imaging approach for early identification of cardiovascular disorders in these patients.

Original language	English
Journal	Clinical Radiology
DOIs	https://doi.org/10.1016/j.crad.2015.03.009
Publication status	Published - 24 Apr 2015

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10.1016/j.crad.2015.03.009

Imaging of cardiovascular risk in patients with
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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title = "Imaging of cardiovascular risk in patients with Turner's syndrome",

abstract = "Turner's syndrome is a disorder defined by an absent or structurally abnormal second X chromosome and affects around 1 in 2000 newborn females. The standardised mortality ratio in Turner's syndrome is around three-times higher than in the general female population, mainly as a result of cardiovascular disorders. Most striking is the early age at which Turner's syndrome patients develop the life-threatening complications of cardiovascular disorders compared to the general population. The cardiovascular risk stratification in Turner's syndrome is challenging and imaging is not systematically used. The aim of this article is to review cardiovascular risks in this group of patients and discuss a systematic imaging approach for early identification of cardiovascular disorders in these patients.",

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AU - Weir-McCall, J R

AU - Webb, D J

AU - van Beek, E J R

AU - Mirsadraee, S

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N2 - Turner's syndrome is a disorder defined by an absent or structurally abnormal second X chromosome and affects around 1 in 2000 newborn females. The standardised mortality ratio in Turner's syndrome is around three-times higher than in the general female population, mainly as a result of cardiovascular disorders. Most striking is the early age at which Turner's syndrome patients develop the life-threatening complications of cardiovascular disorders compared to the general population. The cardiovascular risk stratification in Turner's syndrome is challenging and imaging is not systematically used. The aim of this article is to review cardiovascular risks in this group of patients and discuss a systematic imaging approach for early identification of cardiovascular disorders in these patients.

AB - Turner's syndrome is a disorder defined by an absent or structurally abnormal second X chromosome and affects around 1 in 2000 newborn females. The standardised mortality ratio in Turner's syndrome is around three-times higher than in the general female population, mainly as a result of cardiovascular disorders. Most striking is the early age at which Turner's syndrome patients develop the life-threatening complications of cardiovascular disorders compared to the general population. The cardiovascular risk stratification in Turner's syndrome is challenging and imaging is not systematically used. The aim of this article is to review cardiovascular risks in this group of patients and discuss a systematic imaging approach for early identification of cardiovascular disorders in these patients.

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SN - 0009-9260

JO - Clinical Radiology

JF - Clinical Radiology

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Imaging of cardiovascular risk in patients with Turner's syndrome

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