Abstract
Selective, bioorthogonal and fast labeling of glycoconjugates in living cells is a major challenge for synthetic and cellular biology. Here we report the use imidazolium tagged-mannosamine derivative (ITag-Man) for the non-covalent, rapid and site-specific labeling of sialic acid containing glycoproteins using commercial N-nitrilotriacetate fluorescent reagents in a range of cell lines.
Original language | English |
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Pages (from-to) | 4906-4909 |
Journal | Chemical Communications |
Volume | 52 |
Issue number | 27 |
DOIs | |
Publication status | Published - 7 Apr 2016 |