Immune escape strategies of Borrelia burgdorferi

Bilal Aslam*, Muhammad Atif Nisar, Mohsin Khurshid, Khalid Salamat

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.

Original languageEnglish
Pages (from-to)1219-1237
Number of pages19
JournalFuture Microbiology
Volume12
Issue number13
Early online date15 Sep 2017
DOIs
Publication statusPublished - 1 Oct 2017

Keywords

  • Borrelia burgdorferi
  • immune evasion
  • spirochete

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