Immune escape strategies of Borrelia burgdorferi

Bilal Aslam; Muhammad Atif Nisar; Mohsin Khurshid; Khalid Salamat

doi:10.2217/fmb-2017-0013

Immune escape strategies of Borrelia burgdorferi

Bilal Aslam^*, Muhammad Atif Nisar, Mohsin Khurshid, Khalid Salamat

^*Corresponding author for this work

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Review article › peer-review

Abstract / Description of output

The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.

Original language	English
Pages (from-to)	1219-1237
Number of pages	19
Journal	Future Microbiology
Volume	12
Issue number	13
Early online date	15 Sept 2017
DOIs	https://doi.org/10.2217/fmb-2017-0013
Publication status	Published - 1 Oct 2017

Keywords / Materials (for Non-textual outputs)

Borrelia burgdorferi
immune evasion
spirochete

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10.2217/fmb-2017-0013

Manuscript__Aslam_B_R2__ (002)Accepted author manuscript, 1.81 MB

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title = "Immune escape strategies of Borrelia burgdorferi",

abstract = "The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.",

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author = "Bilal Aslam and Nisar, {Muhammad Atif} and Mohsin Khurshid and Khalid Salamat",

year = "2017",

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doi = "10.2217/fmb-2017-0013",

language = "English",

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TY - JOUR

T1 - Immune escape strategies of Borrelia burgdorferi

AU - Aslam, Bilal

AU - Nisar, Muhammad Atif

AU - Khurshid, Mohsin

AU - Salamat, Khalid

PY - 2017/10/1

Y1 - 2017/10/1

N2 - The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.

AB - The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.

KW - Borrelia burgdorferi

KW - immune evasion

KW - spirochete

UR - http://www.scopus.com/inward/record.url?scp=85030624017&partnerID=8YFLogxK

U2 - 10.2217/fmb-2017-0013

DO - 10.2217/fmb-2017-0013

M3 - Review article

AN - SCOPUS:85030624017

SN - 1746-0913

VL - 12

SP - 1219

EP - 1237

JO - Future Microbiology

JF - Future Microbiology

IS - 13

ER -

Immune escape strategies of Borrelia burgdorferi

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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