Immune-mediated haemolytic anaemia in two sibling cats associated with multicentric lymphoblastic infiltration

D A Gunn-Moore, M J Day, M E Graham, S M Cue, D A Harbour

Research output: Contribution to journalArticlepeer-review

Abstract

Immune-mediated haemolytic anaemia associated with multicentric lymphoblastic infiltration is reported in two sibling cats. Both cats presented at under 16 months of age with clinical signs of acute anaemia. In each case there was autoagglutination, a positive Coombs' test and the anaemia was regenerative. At presentation, both cats were negative for FeLV antigen. In each case, the disease proved fatal within 2 months of the initial diagnosis. In both cases, T-lymphoblastic infiltration of bone marrow, liver and spleen was found at post-mortem examination.
Original languageEnglish
Pages (from-to)209-14
Number of pages6
JournalJournal of Feline Medicine and Surgery
Volume1
Issue number4
DOIs
Publication statusPublished - Dec 1999

Keywords

  • Lymphocyte Activation
  • Bone Marrow
  • Fatal Outcome
  • Animals
  • Cat Diseases
  • Cats
  • Liver
  • Coombs Test
  • Spleen
  • Anemia, Hemolytic, Autoimmune
  • Male
  • T-Lymphocytes

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