Abstract / Description of output
A three-year-old pet ewe was assessed after collapsing, following a four-day history of lethargy, anorexia and discoloured urine. Haematological assessment revealed a regenerative anaemia, with spherocyte-like cells and basophilic structures on the surface of erythrocytes. A haemotrophic mycoplasma was detected in blood using polymerase chain reaction amplification of the 16S rRNA gene followed by denaturing gradient gel electrophoresis. Treatment with enrofloxacin or oxytetracycline achieved short-lived relief of symptoms, whereas tulathromycin was associated in longer lasting control of clinical signs. Haemotrophic Mycoplasma species are an uncommon cause of anaemia in sheep, which until recently had been difficult to diagnose. This report describes a case of immune-mediated haemolytic anaemia associated with infection with an ovine haemotrophic mycoplasma.