Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof

David Gally (Inventor), Arvind Mahajan (Inventor), Christopher Low (Inventor), T.M. McNeilly (Inventor), David G E Smith (Inventor)

Research output: Patent

Abstract

Immunogenic compositions containing Escherichia coli O157:H7 flagella including fusion proteins and methods using the immunogenic compositions are disclosed. Inducing an immune response in an animal to Escherichia coli O157:H7 flagella will result in prevention of colonization by Escherichia coli O157:H7 in the animal or a reduction in the amount of Escherichia coli O157:H7 infecting the animal. The immune composition will prevent or reduce the attachment of Escherichia coli O157:H7 to cells within the animal.
Original languageEnglish
Patent numberEP2201029 A1
Publication statusPublished - 30 Jun 2010

Keywords

  • Flagella H7 EHEC Escherichia coli vaccine mucosal adjuvant

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