Imprinted genes in the placenta - A review

PM Coan; GJ Burton; AC Ferguson-Smith

doi:10.1016/j.placenta.2004.12.009

Imprinted genes in the placenta - A review

PM Coan^*, GJ Burton, AC Ferguson-Smith

^*Corresponding author for this work

Research output: Contribution to journal › Literature review › peer-review

Abstract / Description of output

Imprinted genes are expressed monoallelically depending on their parental origin. High expression of the majority of imprinted genes tested to date has been demonstrated in extraembryonic tissues; placenta and yolk sac. Several mouse models where specific imprinted genes have been disrupted demonstrate that fetal and placental growth may be regulated by imprinted genes, in which paternally expressed genes enhance, and maternally expressed genes restrain, growth. We review the current information on, and suggest possible functional roles for, imprinted genes in placental development. &COPY; 2005 Published by IFPA and Elsevier Ltd.

Original language	English
Pages (from-to)	S10-S20
Number of pages	11
Journal	Placenta
Volume	26
DOIs	https://doi.org/10.1016/j.placenta.2004.12.009
Publication status	Published - Apr 2005
Event	1st Meeting of the Placenta-Association-of-the-Americas/10th International-Federation-of-Placenta-Associations - Pacific Grove, Canada Duration: 25 Sept 2005 → 29 Sept 2005

Keywords / Materials (for Non-textual outputs)

imprinted genes
placenta
development
BECKWITH-WIEDEMANN-SYNDROME
PRADER-WILLI-SYNDROME
GROWTH-FACTOR-II
MOUSE NECDIN GENE
MURINE PLACENTA
IGF-II
P53-MEDIATED APOPTOSIS
EXTRAEMBRYONIC TISSUES
PERINATAL LETHALITY
LABORATORY-ANIMALS

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10.1016/j.placenta.2004.12.009

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title = "Imprinted genes in the placenta - A review",

abstract = "Imprinted genes are expressed monoallelically depending on their parental origin. High expression of the majority of imprinted genes tested to date has been demonstrated in extraembryonic tissues; placenta and yolk sac. Several mouse models where specific imprinted genes have been disrupted demonstrate that fetal and placental growth may be regulated by imprinted genes, in which paternally expressed genes enhance, and maternally expressed genes restrain, growth. We review the current information on, and suggest possible functional roles for, imprinted genes in placental development. &COPY; 2005 Published by IFPA and Elsevier Ltd.",

keywords = "imprinted genes, placenta, development, BECKWITH-WIEDEMANN-SYNDROME, PRADER-WILLI-SYNDROME, GROWTH-FACTOR-II, MOUSE NECDIN GENE, MURINE PLACENTA, IGF-II, P53-MEDIATED APOPTOSIS, EXTRAEMBRYONIC TISSUES, PERINATAL LETHALITY, LABORATORY-ANIMALS",

author = "PM Coan and GJ Burton and AC Ferguson-Smith",

year = "2005",

month = apr,

doi = "10.1016/j.placenta.2004.12.009",

language = "English",

volume = "26",

pages = "S10--S20",

journal = "Placenta",

issn = "0143-4004",

publisher = "W.B. Saunders Ltd",

note = "1st Meeting of the Placenta-Association-of-the-Americas/10th International-Federation-of-Placenta-Associations ; Conference date: 25-09-2005 Through 29-09-2005",

}

TY - JOUR

T1 - Imprinted genes in the placenta - A review

AU - Coan, PM

AU - Burton, GJ

AU - Ferguson-Smith, AC

PY - 2005/4

Y1 - 2005/4

N2 - Imprinted genes are expressed monoallelically depending on their parental origin. High expression of the majority of imprinted genes tested to date has been demonstrated in extraembryonic tissues; placenta and yolk sac. Several mouse models where specific imprinted genes have been disrupted demonstrate that fetal and placental growth may be regulated by imprinted genes, in which paternally expressed genes enhance, and maternally expressed genes restrain, growth. We review the current information on, and suggest possible functional roles for, imprinted genes in placental development. &COPY; 2005 Published by IFPA and Elsevier Ltd.

AB - Imprinted genes are expressed monoallelically depending on their parental origin. High expression of the majority of imprinted genes tested to date has been demonstrated in extraembryonic tissues; placenta and yolk sac. Several mouse models where specific imprinted genes have been disrupted demonstrate that fetal and placental growth may be regulated by imprinted genes, in which paternally expressed genes enhance, and maternally expressed genes restrain, growth. We review the current information on, and suggest possible functional roles for, imprinted genes in placental development. &COPY; 2005 Published by IFPA and Elsevier Ltd.

KW - imprinted genes

KW - placenta

KW - development

KW - BECKWITH-WIEDEMANN-SYNDROME

KW - PRADER-WILLI-SYNDROME

KW - GROWTH-FACTOR-II

KW - MOUSE NECDIN GENE

KW - MURINE PLACENTA

KW - IGF-II

KW - P53-MEDIATED APOPTOSIS

KW - EXTRAEMBRYONIC TISSUES

KW - PERINATAL LETHALITY

KW - LABORATORY-ANIMALS

U2 - 10.1016/j.placenta.2004.12.009

DO - 10.1016/j.placenta.2004.12.009

M3 - Literature review

SN - 0143-4004

VL - 26

SP - S10-S20

JO - Placenta

JF - Placenta

T2 - 1st Meeting of the Placenta-Association-of-the-Americas/10th International-Federation-of-Placenta-Associations

Y2 - 25 September 2005 through 29 September 2005

ER -

Imprinted genes in the placenta - A review

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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