Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol

Ronan O'Carroll; Martin Dennis; Marie Johnston; Cathie Sudlow

doi:10.1186/1471-2377-10-15

Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol

Ronan O'Carroll, Martin Dennis, Marie Johnston, Cathie Sudlow

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Background: Adherence to therapies is a primary determinant of treatment success, yet the World Health Organisation estimate that only 50% of patients who suffer from chronic diseases adhere to treatment recommendations. In a previous project, we found that 30% of stroke patients reported sub-optimal medication adherence, and this was associated with younger age, greater cognitive impairment, lower perceptions of medication benefits and higher specific concerns about medication. We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke.

Methods/Design: Thirty patients will be allocated to a brief intervention (2 sessions) and 30 to treatment as usual. The primary outcome will be adherence measured over 3 months using Medication Event Monitoring System (MEMS) pill containers which electronically record openings. Secondary outcomes will include self reported adherence and blood pressure.

Discussion: This study shall also assess uptake/attrition, feasibility, ease of understanding and acceptability of this complex intervention.

Original language	English
Article number	15
Pages (from-to)	-
Number of pages	9
Journal	Bmc neurology
Volume	10
DOIs	https://doi.org/10.1186/1471-2377-10-15
Publication status	Published - 24 Feb 2010

Keywords / Materials (for Non-textual outputs)

SECONDARY PREVENTION
MYOCARDIAL-INFARCTION
ISCHEMIC-STROKE
INTERVENTION
BELIEFS
DISEASE

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10.1186/1471-2377-10-15

Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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http://www.biomedcentral.com/1471-2377/10/15

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abstract = "Background: Adherence to therapies is a primary determinant of treatment success, yet the World Health Organisation estimate that only 50% of patients who suffer from chronic diseases adhere to treatment recommendations. In a previous project, we found that 30% of stroke patients reported sub-optimal medication adherence, and this was associated with younger age, greater cognitive impairment, lower perceptions of medication benefits and higher specific concerns about medication. We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke.Methods/Design: Thirty patients will be allocated to a brief intervention (2 sessions) and 30 to treatment as usual. The primary outcome will be adherence measured over 3 months using Medication Event Monitoring System (MEMS) pill containers which electronically record openings. Secondary outcomes will include self reported adherence and blood pressure.Discussion: This study shall also assess uptake/attrition, feasibility, ease of understanding and acceptability of this complex intervention.",

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AU - O'Carroll, Ronan

AU - Dennis, Martin

AU - Johnston, Marie

AU - Sudlow, Cathie

PY - 2010/2/24

Y1 - 2010/2/24

N2 - Background: Adherence to therapies is a primary determinant of treatment success, yet the World Health Organisation estimate that only 50% of patients who suffer from chronic diseases adhere to treatment recommendations. In a previous project, we found that 30% of stroke patients reported sub-optimal medication adherence, and this was associated with younger age, greater cognitive impairment, lower perceptions of medication benefits and higher specific concerns about medication. We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke.Methods/Design: Thirty patients will be allocated to a brief intervention (2 sessions) and 30 to treatment as usual. The primary outcome will be adherence measured over 3 months using Medication Event Monitoring System (MEMS) pill containers which electronically record openings. Secondary outcomes will include self reported adherence and blood pressure.Discussion: This study shall also assess uptake/attrition, feasibility, ease of understanding and acceptability of this complex intervention.

AB - Background: Adherence to therapies is a primary determinant of treatment success, yet the World Health Organisation estimate that only 50% of patients who suffer from chronic diseases adhere to treatment recommendations. In a previous project, we found that 30% of stroke patients reported sub-optimal medication adherence, and this was associated with younger age, greater cognitive impairment, lower perceptions of medication benefits and higher specific concerns about medication. We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke.Methods/Design: Thirty patients will be allocated to a brief intervention (2 sessions) and 30 to treatment as usual. The primary outcome will be adherence measured over 3 months using Medication Event Monitoring System (MEMS) pill containers which electronically record openings. Secondary outcomes will include self reported adherence and blood pressure.Discussion: This study shall also assess uptake/attrition, feasibility, ease of understanding and acceptability of this complex intervention.

KW - SECONDARY PREVENTION

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KW - BELIEFS

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Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol

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Keywords / Materials (for Non-textual outputs)

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