In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque

CM Moran; J Ross; C Cunningham; M Butler; WN McDicken

In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque

CM Moran^*, J Ross, C Cunningham, M Butler, WN McDicken

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper describes the measurement of the acoustical properties of an in-house contrast agent at 40MHz. In addition, it compares the measured acoustical properties from the agent to three commercial agents (Definity, Optison and SonoVue) at 40MHz. A Boston Scientific Clear-View Ultra intravascular ultrasound scanner with a 40MHz, 2.5Fr Atlantis SR Plus catheter is used.

Mean backscatter power was measured and referenced to the echo from a water-air interface. Mean backscatter power from the in-house ultrasonic contrast agent was found to be -20.53 +/- 0.39dB at 40MHz. Measured mean backscatter power at 40MHz for Definity, Optison and SonoVue was -25.7dB +/- 2.6, -26.9 +/- 2.2dB and -25.07 +/- 1.5dB respectively.

Original language	English
Title of host publication	2004 IEEE Ultrasonics Symposium, Vols 1-3
Editors	MP Yuhas
Place of Publication	NEW YORK
Publisher	Institute of Electrical and Electronics Engineers
Pages	1395-1397
Number of pages	3
ISBN (Print)	0-7803-8413-X
Publication status	Published - 2004
Event	IEEE Ultrasonics Symposium - Montreal, Canada Duration: 23 Aug 2004 → 27 Aug 2004

Publication series

Name	ULTRASONICS SYMPOSIUM
Publisher	IEEE
ISSN (Print)	1051-0117

Conference

Conference	IEEE Ultrasonics Symposium
Country/Territory	Canada
Period	23/08/04 → 27/08/04

Keywords / Materials (for Non-textual outputs)

component
ultrasonic contrast agents
high frequency
CONTRAST AGENT

Cite this

@inproceedings{6ef8306171044c1f8a960eec3ddc662a,

title = "In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque",

abstract = "This paper describes the measurement of the acoustical properties of an in-house contrast agent at 40MHz. In addition, it compares the measured acoustical properties from the agent to three commercial agents (Definity, Optison and SonoVue) at 40MHz. A Boston Scientific Clear-View Ultra intravascular ultrasound scanner with a 40MHz, 2.5Fr Atlantis SR Plus catheter is used.Mean backscatter power was measured and referenced to the echo from a water-air interface. Mean backscatter power from the in-house ultrasonic contrast agent was found to be -20.53 +/- 0.39dB at 40MHz. Measured mean backscatter power at 40MHz for Definity, Optison and SonoVue was -25.7dB +/- 2.6, -26.9 +/- 2.2dB and -25.07 +/- 1.5dB respectively.",

keywords = "component, ultrasonic contrast agents, high frequency, CONTRAST AGENT",

author = "CM Moran and J Ross and C Cunningham and M Butler and WN McDicken",

year = "2004",

language = "English",

isbn = "0-7803-8413-X",

series = "ULTRASONICS SYMPOSIUM",

publisher = "Institute of Electrical and Electronics Engineers",

pages = "1395--1397",

editor = "MP Yuhas",

booktitle = "2004 IEEE Ultrasonics Symposium, Vols 1-3",

address = "United States",

note = "IEEE Ultrasonics Symposium ; Conference date: 23-08-2004 Through 27-08-2004",

}

Moran, CM, Ross, J, Cunningham, C, Butler, M & McDicken, WN 2004, In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque. in MP Yuhas (ed.), 2004 IEEE Ultrasonics Symposium, Vols 1-3. ULTRASONICS SYMPOSIUM, Institute of Electrical and Electronics Engineers, NEW YORK, pp. 1395-1397, IEEE Ultrasonics Symposium, Canada, 23/08/04.

In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque. / Moran, CM; Ross, J; Cunningham, C et al.
2004 IEEE Ultrasonics Symposium, Vols 1-3. ed. / MP Yuhas. NEW YORK: Institute of Electrical and Electronics Engineers, 2004. p. 1395-1397 (ULTRASONICS SYMPOSIUM).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque

AU - Moran, CM

AU - Ross, J

AU - Cunningham, C

AU - Butler, M

AU - McDicken, WN

PY - 2004

Y1 - 2004

N2 - This paper describes the measurement of the acoustical properties of an in-house contrast agent at 40MHz. In addition, it compares the measured acoustical properties from the agent to three commercial agents (Definity, Optison and SonoVue) at 40MHz. A Boston Scientific Clear-View Ultra intravascular ultrasound scanner with a 40MHz, 2.5Fr Atlantis SR Plus catheter is used.Mean backscatter power was measured and referenced to the echo from a water-air interface. Mean backscatter power from the in-house ultrasonic contrast agent was found to be -20.53 +/- 0.39dB at 40MHz. Measured mean backscatter power at 40MHz for Definity, Optison and SonoVue was -25.7dB +/- 2.6, -26.9 +/- 2.2dB and -25.07 +/- 1.5dB respectively.

AB - This paper describes the measurement of the acoustical properties of an in-house contrast agent at 40MHz. In addition, it compares the measured acoustical properties from the agent to three commercial agents (Definity, Optison and SonoVue) at 40MHz. A Boston Scientific Clear-View Ultra intravascular ultrasound scanner with a 40MHz, 2.5Fr Atlantis SR Plus catheter is used.Mean backscatter power was measured and referenced to the echo from a water-air interface. Mean backscatter power from the in-house ultrasonic contrast agent was found to be -20.53 +/- 0.39dB at 40MHz. Measured mean backscatter power at 40MHz for Definity, Optison and SonoVue was -25.7dB +/- 2.6, -26.9 +/- 2.2dB and -25.07 +/- 1.5dB respectively.

KW - component

KW - ultrasonic contrast agents

KW - high frequency

KW - CONTRAST AGENT

M3 - Conference contribution

SN - 0-7803-8413-X

T3 - ULTRASONICS SYMPOSIUM

SP - 1395

EP - 1397

BT - 2004 IEEE Ultrasonics Symposium, Vols 1-3

A2 - Yuhas, MP

PB - Institute of Electrical and Electronics Engineers

CY - NEW YORK

T2 - IEEE Ultrasonics Symposium

Y2 - 23 August 2004 through 27 August 2004

ER -

In vitro 40MHz ultrasonic characterisation of inhouse liposomal dispersions developed for targeting atherosclerotic plaque

Abstract

Publication series

Conference

Keywords / Materials (for Non-textual outputs)

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Cite this