In vitro modeling of central nervous system myelination and remyelination

Andrew A Jarjour; Hui Zhang; Nina Bauer; Charles Ffrench-Constant; Anna Williams

doi:10.1002/glia.21231

In vitro modeling of central nervous system myelination and remyelination

Andrew A Jarjour, Hui Zhang, Nina Bauer, Charles Ffrench-Constant, Anna Williams

Research output: Contribution to journal › Literature review › peer-review

Abstract

This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future.

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	Glia
Volume	60
Issue number	1
DOIs	https://doi.org/10.1002/glia.21231
Publication status	Published - 2012

Access to Document

10.1002/glia.21231

Cite this

@article{75771eb3b8ce4024b73dda0bede7640a,

title = "In vitro modeling of central nervous system myelination and remyelination",

abstract = "This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future.",

author = "Jarjour, {Andrew A} and Hui Zhang and Nina Bauer and Charles Ffrench-Constant and Anna Williams",

note = "Copyright {\textcopyright} 2011 Wiley Periodicals, Inc.",

year = "2012",

doi = "10.1002/glia.21231",

language = "English",

volume = "60",

pages = "1--12",

journal = "Glia",

issn = "1098-1136",

publisher = "Wiley",

number = "1",

}

TY - JOUR

T1 - In vitro modeling of central nervous system myelination and remyelination

AU - Jarjour, Andrew A

AU - Zhang, Hui

AU - Bauer, Nina

AU - Ffrench-Constant, Charles

AU - Williams, Anna

PY - 2012

Y1 - 2012

N2 - This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future.

AB - This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future.

UR - http://www.scopus.com/inward/record.url?scp=81155150053&partnerID=8YFLogxK

U2 - 10.1002/glia.21231

DO - 10.1002/glia.21231

M3 - Literature review

C2 - 21858876

SN - 1098-1136

VL - 60

SP - 1

EP - 12

JO - Glia

JF - Glia

IS - 1

ER -

In vitro modeling of central nervous system myelination and remyelination

Abstract

Access to Document

Other files and links

Fingerprint

PhD STUDENT - JOANNE SIMPSON - Supervisor MOHINI GRAY

Trf of Millstein award from Univ of Cambridge : A Functional Proteomic Screen of Myelination

Cite this

In vitro modeling of central nervous system myelination and remyelination

Abstract

Access to Document

Other files and links

Fingerprint

Projects

PhD STUDENT - JOANNE SIMPSON - Supervisor MOHINI GRAY

Trf of Millstein award from Univ of Cambridge : A Functional Proteomic Screen of Myelination

Cite this