Incidental Findings on Brain MR Imaging in Older Community-Dwelling Subjects Are Common but Serious Medical Consequences Are Rare: A Cohort Study

Elaine M Sandeman; Maria Del Carmen Valdes Hernandez; Zoe Morris; Mark E Bastin; Catherine Murray; Alan J  Gow; Janie Corley; Ross Henderson; Ian Deary; John M Starr; Joanna M Wardlaw

doi:10.1371/journal.pone.0071467

Incidental Findings on Brain MR Imaging in Older Community-Dwelling Subjects Are Common but Serious Medical Consequences Are Rare: A Cohort Study

Elaine M Sandeman, Maria Del Carmen Valdes Hernandez, Zoe Morris, Mark E Bastin, Catherine Murray, Alan J Gow, Janie Corley, Ross Henderson, Ian Deary, John M Starr, Joanna M Wardlaw

Research output: Contribution to journal › Article › peer-review

Abstract

Incidental findings in neuroimaging occur in 3% of volunteers. Most data come from young subjects. Data on their occurrence in older subjects and their medical, lifestyle and financial consequences are lacking. We determined the prevalence and medical consequences of incidental findings found in community-dwelling older subjects on brain magnetic resonance imaging.

Original language	English
Article number	e71467
Number of pages	8
Journal	PLoS ONE
Volume	8
Issue number	8
DOIs	https://doi.org/10.1371/journal.pone.0071467
Publication status	Published - 15 Aug 2013

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10.1371/journal.pone.0071467

Incidental Findings on Brain MR Imaging in Older Community-Dwelling Subjects Are Common but Serious Medical Consequences Are Rare
Copyright: © 2013 Sandeman et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071467

RA2661 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2. Main Budget.
Deary, I. (Principal Investigator), Gale, C. (Co-investigator), Holmes, M. (Co-investigator), Logie, P. (Co-investigator), Maclullich, A. (Co-investigator), Porteous, D. (Co-investigator), Seckl, J. (Co-investigator), Starr, J. (Co-investigator), Wardlaw, J. (Co-investigator) & Okely, J. (Researcher)
1/09/13 → 31/08/19
Project: Research
Brain White mater imaging and cognitive ageing in the Lothian Birth Cohort of 1936:II
Deary, I. (Principal Investigator), Bastin, M. (Co-investigator), Penke, L. (Co-investigator), Starr, J. (Co-investigator) & Wardlaw, J. (Co-investigator)
MRC
8/06/11 → 7/03/15
Project: Research
Disconnected Mind [Phase 2]
Wardlaw, J. (Principal Investigator)
UK-based charities
1/01/11 → 31/03/16
Project: Research

Cite this

Sandeman, E. M., Valdes Hernandez, M. D. C., Morris, Z., Bastin, M. E., Murray, C., Gow, A. J., Corley, J., Henderson, R., Deary, I., Starr, J. M., & Wardlaw, J. M. (2013). Incidental Findings on Brain MR Imaging in Older Community-Dwelling Subjects Are Common but Serious Medical Consequences Are Rare: A Cohort Study. PLoS ONE, 8(8), Article e71467. https://doi.org/10.1371/journal.pone.0071467

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abstract = "Incidental findings in neuroimaging occur in 3% of volunteers. Most data come from young subjects. Data on their occurrence in older subjects and their medical, lifestyle and financial consequences are lacking. We determined the prevalence and medical consequences of incidental findings found in community-dwelling older subjects on brain magnetic resonance imaging.",

author = "Sandeman, {Elaine M} and {Valdes Hernandez}, {Maria Del Carmen} and Zoe Morris and Bastin, {Mark E} and Catherine Murray and Gow, {Alan J} and Janie Corley and Ross Henderson and Ian Deary and Starr, {John M} and Wardlaw, {Joanna M}",

note = " Funding: Medical Research Council [G1001245, G0700704] Funding from the Biotechnology and Biological Sciences Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, and the Medical Research Council is gratefully acknowledged.",

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doi = "10.1371/journal.pone.0071467",

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Sandeman, EM, Valdes Hernandez, MDC, Morris, Z, Bastin, ME, Murray, C, Gow, AJ, Corley, J, Henderson, R, Deary, I, Starr, JM & Wardlaw, JM 2013, 'Incidental Findings on Brain MR Imaging in Older Community-Dwelling Subjects Are Common but Serious Medical Consequences Are Rare: A Cohort Study', PLoS ONE, vol. 8, no. 8, e71467. https://doi.org/10.1371/journal.pone.0071467

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AU - Bastin, Mark E

AU - Murray, Catherine

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AU - Corley, Janie

AU - Henderson, Ross

AU - Deary, Ian

AU - Starr, John M

AU - Wardlaw, Joanna M

N1 - Funding: Medical Research Council [G1001245, G0700704] Funding from the Biotechnology and Biological Sciences Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, and the Medical Research Council is gratefully acknowledged.

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Y1 - 2013/8/15

N2 - Incidental findings in neuroimaging occur in 3% of volunteers. Most data come from young subjects. Data on their occurrence in older subjects and their medical, lifestyle and financial consequences are lacking. We determined the prevalence and medical consequences of incidental findings found in community-dwelling older subjects on brain magnetic resonance imaging.

AB - Incidental findings in neuroimaging occur in 3% of volunteers. Most data come from young subjects. Data on their occurrence in older subjects and their medical, lifestyle and financial consequences are lacking. We determined the prevalence and medical consequences of incidental findings found in community-dwelling older subjects on brain magnetic resonance imaging.

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DO - 10.1371/journal.pone.0071467

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JF - PLoS ONE

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Incidental Findings on Brain MR Imaging in Older Community-Dwelling Subjects Are Common but Serious Medical Consequences Are Rare: A Cohort Study

Abstract

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Projects

RA2661 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2. Main Budget.

Brain White mater imaging and cognitive ageing in the Lothian Birth Cohort of 1936:II

Disconnected Mind [Phase 2]

Cite this