Inclusion or exclusion of intratumoral vessels in relative cerebral blood volume characterization in low-grade gliomas: does it make a difference?

G Brasil Caseiras, J S Thornton, T Yousry, C Benton, J Rees, Adam Waldman, H R Jäger

Research output: Contribution to journalArticlepeer-review

Abstract

We assessed the influence of inclusion (method 1) and exclusion (method 2) of intratumoral vessels when determining maximum relative cerebral blood volume (rCBVmax) in 3 types of low-grade gliomas (LGGs): astrocytomas, oligoastrocytomas, and oligodendrogliomas. Method 1 yielded significantly higher mean rCBVmax than method 2. However, only method 2 demonstrated a significant (P = .026) association between rCBVmax and membership of a differently ranked histologic category. Exclusion of intratumoral vessels appears, therefore, preferable when determining rCBVmax in LGGs.

Original languageEnglish
Pages (from-to)1140-1
Number of pages2
JournalAmerican Journal of Neuroradiology
Volume29
Issue number6
DOIs
Publication statusPublished - 29 Jun 2008

Keywords

  • Blood Volume
  • Brain Neoplasms
  • Cerebrovascular Circulation
  • Glioma
  • Humans
  • Image Interpretation, Computer-Assisted
  • Magnetic Resonance Imaging
  • Neovascularization, Pathologic
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Journal Article

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