Increased expression of minichromosome maintenance protein 2 in active inflammatory bowel disease

R J Davies, I S Scott, L S Morris, S M Rushbrook, K Bird, S L Vowler, M Arends, R Miller, N Coleman

Research output: Contribution to journalArticlepeer-review

Abstract

Minichromosome maintenance protein 2 (Mcm2) is an accurate indicator of cell cycle entry in tissue samples, but its expression in inflammatory bowel disease (IBD) has not previously been investigated. We have used immunohistochemistry to assess the expression of Mcm2, in comparison to the existing proliferation marker Ki-67, in active IBD and IBD without inflammatory activity.
Original languageEnglish
Pages (from-to)103-10
Number of pages8
JournalColorectal Disease
Volume6
Issue number2
Publication statusPublished - Mar 2004

Keywords

  • Cell Cycle Proteins
  • Colitis, Ulcerative
  • Colon
  • Crohn Disease
  • Humans
  • Inflammatory Bowel Diseases
  • Intestinal Mucosa
  • Ki-67 Antigen

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