Induced pluripotent stem cell technology and stem cell therapy for diabetes (Review)

Robert J. Drummond, Tilo Kunath, P. Joseph Mee, James A. Ross

Research output: Contribution to journalArticlepeer-review

Abstract

Although diabetes can be managed clinically with the use of insulin injections, it remains an incurable and inconvenient disorder. In the long-term, it is associated with a number of clinical complications, such as cardiovascular disease, resulting in a desire for the development of new methodologies to replace defective cells and provide a lasting normality without the need for drug treatment. Stern cells, including induced pluripotent stem cells, offer the possibility of generating cells suitable for transplantation due to their capacity to differentiate into all tissue lineages. However, many issues must be addressed before this type of treatment becomes a reality, including the need for a greater understanding of the underlying biology involved in the onset of diabetes.

Original languageEnglish
Pages (from-to)3-7
Number of pages5
JournalExperimental and therapeutic medicine
Volume2
Issue number1
DOIs
Publication statusPublished - 2011

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