Inflammatory activity in Crohn's disease: CE-US

Vincenzo Migaleddu; Emilio Quaia; Domenico Scanu; Serra Carla; Michele Bertolotto; Girolamo Campisi; Danilo Sirigu; Giuseppe Virgilio

doi:10.1007/s00261-010-9622-8

Inflammatory activity in Crohn's disease: CE-US

Vincenzo Migaleddu, Emilio Quaia, Domenico Scanu, Serra Carla, Michele Bertolotto, Girolamo Campisi, Danilo Sirigu, Giuseppe Virgilio

Research output: Contribution to journal › Article › peer-review

Abstract

The evaluation of inflammatory activity in Crohn's disease (CD), a crucial aspect of treatment planning and monitoring, is currently based on a sum of clinical data and imaging findings. Among the contrast enhanced cross-sectional imaging techniques (CE-US, CE-CT, CE-MR), CE-US is less invasive, more comfortable for the patient, and has significant diagnostic accuracy. In addition, it is a portable, easily repeatable, well tolerated, and ionizing radiation-free imaging modality. CE-US has been introduced as effective method in the quantitative and qualitative evaluation of CD inflammatory activity. CE-US might help in characterizing bowel-wall thickening by differentiating inflammatory neovascularisation, edema, and fibrosis. The recent chance to evaluate the bowel-wall stiffness by US elastography imaging could allow further assessment of fibrosis that characterizes the evolution of the inflammatory activity.

Original language	English
Pages (from-to)	142-8
Number of pages	7
Journal	Abdominal Imaging
Volume	36
Issue number	2
DOIs	https://doi.org/10.1007/s00261-010-9622-8
Publication status	Published - Apr 2011

Keywords

Contrast Media
Crohn Disease
Humans
Inflammation
Microbubbles
Ultrasonography

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10.1007/s00261-010-9622-8

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title = "Inflammatory activity in Crohn's disease: CE-US",

abstract = "The evaluation of inflammatory activity in Crohn's disease (CD), a crucial aspect of treatment planning and monitoring, is currently based on a sum of clinical data and imaging findings. Among the contrast enhanced cross-sectional imaging techniques (CE-US, CE-CT, CE-MR), CE-US is less invasive, more comfortable for the patient, and has significant diagnostic accuracy. In addition, it is a portable, easily repeatable, well tolerated, and ionizing radiation-free imaging modality. CE-US has been introduced as effective method in the quantitative and qualitative evaluation of CD inflammatory activity. CE-US might help in characterizing bowel-wall thickening by differentiating inflammatory neovascularisation, edema, and fibrosis. The recent chance to evaluate the bowel-wall stiffness by US elastography imaging could allow further assessment of fibrosis that characterizes the evolution of the inflammatory activity.",

keywords = "Contrast Media, Crohn Disease, Humans, Inflammation, Microbubbles, Ultrasonography",

author = "Vincenzo Migaleddu and Emilio Quaia and Domenico Scanu and Serra Carla and Michele Bertolotto and Girolamo Campisi and Danilo Sirigu and Giuseppe Virgilio",

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T2 - CE-US

AU - Migaleddu, Vincenzo

AU - Quaia, Emilio

AU - Scanu, Domenico

AU - Carla, Serra

AU - Bertolotto, Michele

AU - Campisi, Girolamo

AU - Sirigu, Danilo

AU - Virgilio, Giuseppe

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AB - The evaluation of inflammatory activity in Crohn's disease (CD), a crucial aspect of treatment planning and monitoring, is currently based on a sum of clinical data and imaging findings. Among the contrast enhanced cross-sectional imaging techniques (CE-US, CE-CT, CE-MR), CE-US is less invasive, more comfortable for the patient, and has significant diagnostic accuracy. In addition, it is a portable, easily repeatable, well tolerated, and ionizing radiation-free imaging modality. CE-US has been introduced as effective method in the quantitative and qualitative evaluation of CD inflammatory activity. CE-US might help in characterizing bowel-wall thickening by differentiating inflammatory neovascularisation, edema, and fibrosis. The recent chance to evaluate the bowel-wall stiffness by US elastography imaging could allow further assessment of fibrosis that characterizes the evolution of the inflammatory activity.

KW - Contrast Media

KW - Crohn Disease

KW - Humans

KW - Inflammation

KW - Microbubbles

KW - Ultrasonography

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JO - Abdominal Imaging

JF - Abdominal Imaging

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Inflammatory activity in Crohn's disease: CE-US

Abstract

Keywords

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