Inhaled beclomethasone dipropionate stepping-up asthma care

Aziz Sheikh

doi:10.1093/med/9780199651559.003.0042

Inhaled beclomethasone dipropionate stepping-up asthma care

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Abstract / Description of output

Beclomethasone dipropionate was used in pressurized aerosols for the treatment of 60 cases of chronic allergic asthma for up to 15 months. Twenty-eight out of 37 cases were transferred to this treatment after being dependent on oral steroids for up to 16 years. Nineteen out of 23 other asthmatics not dependent on steroids were also completely controlled. No biochemical evidence of adrenal suppression was found. Steroid withdrawal symptoms were often a problem, suggesting absence of systemic absorption. The precise mode of action and metabolic fate of this corticosteroid are not yet known.

Original language	English
Title of host publication	Landmark Papers in Allergy: Seminal Papers in Allergy with Expert Commentaries
Editors	Aziz Sheikh, Thomas Platts-Mills, Allison Worth
Publisher	Oxford University Press
Chapter	42
ISBN (Print)	9780199651559
DOIs	https://doi.org/10.1093/med/9780199651559.003.0042
Publication status	Published - Feb 2013

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10.1093/med/9780199651559.003.0042

Cite this

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title = "Inhaled beclomethasone dipropionate stepping-up asthma care",

abstract = "Beclomethasone dipropionate was used in pressurized aerosols for the treatment of 60 cases of chronic allergic asthma for up to 15 months. Twenty-eight out of 37 cases were transferred to this treatment after being dependent on oral steroids for up to 16 years. Nineteen out of 23 other asthmatics not dependent on steroids were also completely controlled. No biochemical evidence of adrenal suppression was found. Steroid withdrawal symptoms were often a problem, suggesting absence of systemic absorption. The precise mode of action and metabolic fate of this corticosteroid are not yet known.",

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AB - Beclomethasone dipropionate was used in pressurized aerosols for the treatment of 60 cases of chronic allergic asthma for up to 15 months. Twenty-eight out of 37 cases were transferred to this treatment after being dependent on oral steroids for up to 16 years. Nineteen out of 23 other asthmatics not dependent on steroids were also completely controlled. No biochemical evidence of adrenal suppression was found. Steroid withdrawal symptoms were often a problem, suggesting absence of systemic absorption. The precise mode of action and metabolic fate of this corticosteroid are not yet known.

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M3 - Chapter

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BT - Landmark Papers in Allergy: Seminal Papers in Allergy with Expert Commentaries

A2 - Sheikh, Aziz

A2 - Platts-Mills, Thomas

A2 - Worth, Allison

PB - Oxford University Press

ER -

Inhaled beclomethasone dipropionate stepping-up asthma care

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