Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

Dolors Puigoriol-Illamola; Júlia Companys-Alemany; Kris Mcguire; Natalie Z. M. Homer; Rosana Leiva; Santiago Vázquez; Damian J. Mole; Christian Griñán-Ferré; Mercè Pallàs

doi:10.3390/ph14101040

Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

Dolors Puigoriol-Illamola, Júlia Companys-Alemany, Kris Mcguire, Natalie Z. M. Homer, Rosana Leiva, Santiago Vázquez, Damian J. Mole, Christian Griñán-Ferré, Mercè Pallàs^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1040
Journal	Pharmaceuticals
Volume	14
Issue number	10
DOIs	https://doi.org/10.3390/ph14101040
Publication status	Published - 13 Oct 2021

Keywords / Materials (for Non-textual outputs)

glucocorticoids
stress
target engagement
Aging
epigenetics
oxidative stress
inflammation
neurodegeneration
Cognition

Access to Document

10.3390/ph14101040

pharmaceuticals-14-01040Final published version, 3.28 MBLicence: Creative Commons: Attribution (CC-BY)

https://www.mdpi.com/1424-8247/14/10/1040Licence: Creative Commons: Attribution (CC-BY)

Edinburgh Clinical Research Facility Mass Spectrometry Core in the QMRI
Natalie Homer (Manager), Scott Denham (Other) & Jo Simpson (Other)
Centre for Cardiovascular Science
Facility/equipment: Facility

Cite this

@article{188b1e38a3c141349ea090f78b98f828,

title = "Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice",

keywords = "glucocorticoids, stress, target engagement, Aging, epigenetics, oxidative stress, inflammation, neurodegeneration, Cognition",

author = "Dolors Puigoriol-Illamola and J{\'u}lia Companys-Alemany and Kris Mcguire and Homer, {Natalie Z. M.} and Rosana Leiva and Santiago V{\'a}zquez and Mole, {Damian J.} and Christian Gri{\~n}{\'a}n-Ferr{\'e} and Merc{\`e} Pall{\`a}s",

year = "2021",

month = oct,

day = "13",

doi = "10.3390/ph14101040",

language = "English",

volume = "14",

pages = "1040",

journal = "Pharmaceuticals",

issn = "1424-8247",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "10",

}

TY - JOUR

T1 - Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

AU - Puigoriol-Illamola, Dolors

AU - Companys-Alemany, Júlia

AU - Mcguire, Kris

AU - Homer, Natalie Z. M.

AU - Leiva, Rosana

AU - Vázquez, Santiago

AU - Mole, Damian J.

AU - Griñán-Ferré, Christian

AU - Pallàs, Mercè

PY - 2021/10/13

Y1 - 2021/10/13

KW - glucocorticoids

KW - stress

KW - target engagement

KW - Aging

KW - epigenetics

KW - oxidative stress

KW - inflammation

KW - neurodegeneration

KW - Cognition

U2 - 10.3390/ph14101040

DO - 10.3390/ph14101040

M3 - Article

SN - 1424-8247

VL - 14

SP - 1040

JO - Pharmaceuticals

JF - Pharmaceuticals

IS - 10

ER -

Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

Keywords / Materials (for Non-textual outputs)

Access to Document

Equipment

Edinburgh Clinical Research Facility Mass Spectrometry Core in the QMRI

Cite this