Innate immunity and the pneumococcus

Gavin K Paterson, Tim J Mitchell

Research output: Contribution to journalReview articlepeer-review

Abstract

The innate immune system provides a non-specific first line of defence against microbes and is crucial both in the development and effector stages of subsequent adaptive immune responses. Consistent with its importance, study of the innate immune system is a broad and fast-moving field. Here we provide an overview of the recent key advances made in this area with relation to the important pathogen Streptococcus pneumoniae (the pneumococcus).

Original languageEnglish
Pages (from-to)285-93
Number of pages9
JournalMicrobiology
Volume152
Issue numberPt 2
DOIs
Publication statusE-pub ahead of print - 1 Feb 2006

Keywords

  • Humans
  • Immunity, Innate/physiology
  • Pneumococcal Infections/immunology
  • Pneumococcal Vaccines/administration & dosage
  • Streptococcus pneumoniae
  • Toll-Like Receptors/physiology

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