Insights into piezophily from genetic studies on the deep-sea bacterium, Photobacterium profundum SS9

Ziad W. El-Hajj, David Allcock, Theodora Tryfona, Federico M. Lauro, Lindsay Sawyer, Douglas H. Bartlett, Gail P. Ferguson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The deep-sea bacterium, Photobacterium profundum SS9, has been adopted as a model organism to understand the molecular basis of cold-adapted high-pressure-loving (piezophilic) growth. Despite growing optimally at 28 MPa (15 degrees C), P. profundum SS9 can grow over a wide range of pressures and temperatures. The ability to grow at atmospheric pressure has enabled a limited set of genetic tools to be developed, which has provided genetic insights into the mechanism of piezophilic growth in P. profundum SS9. This review focuses on how genetic studies have uncovered the importance of processes affecting the DNA and the bacterial cell envelope in the piezophilic growth of P. profundum SS9. In addition, a method was developed to assess quantitative piezophilic colony growth of P. profundum SS9 on solid agar. Future studies, using this methodology, could provide novel insights into the molecular basis of piezophilic, surface-attached growth.

Original languageEnglish
Title of host publicationHIGH-PRESSURE BIOSCIENCE AND BIOTECHNOLOGY
EditorsDH Bartlett
Place of PublicationOXFORD
PublisherBlackwell Publishing Ltd
Pages143-148
Number of pages6
ISBN (Print)978-1-57331-771-9
DOIs
Publication statusPublished - 2010
Event5th International High-Pressure Bioscience and Biotechnology Conference - La Jolla
Duration: 15 Sep 200819 Sep 2008

Conference

Conference5th International High-Pressure Bioscience and Biotechnology Conference
CityLa Jolla
Period15/09/0819/09/08

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