Inspection time, psychometric intelligence and clinical estimates of cognitive ability in presenile Alzheimer's disease and Korsakoff's psychosis.

I J Deary, R Hunter, S J Langan, G M Goodwin

Research output: Contribution to journalArticlepeer-review

Abstract

Ten pre-senile Alzheimer's patients, 11 patients with Korsakoff's psychosis and 11 age- and pre-morbid intelligence-matched controls were given a test of Inspection Time, which estimates the efficiency of visual encoding or iconic memory. Alzheimer's patients had impaired Inspection Time while the Korsakoff group performed very similarly to the controls. Inspection Time performance correlated significantly with psychometric tests of cognitive ability and with clinical tests of cognitive ability (Mini Mental State Examination and Cambridge Mental Disorders of the Elderly Examination). The early stage of information processing measured by the Inspection Time procedure appears to be damaged by the Alzheimer's disease process, and to impose a rate-limiting effect on a wide variety of mental tests.

Original languageEnglish
Pages (from-to)2543-2554
Number of pages12
JournalBrain
Volume114
Publication statusPublished - Dec 1991

Keywords

  • PREMORBID INTELLIGENCE
  • MENTAL-RETARDATION
  • DEMENTIA
  • DIAGNOSIS

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