TY - JOUR
T1 - Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins
AU - Seeger, Michael
AU - Hartmann-Petersen, Rasmus
AU - Wilkinson, Caroline R M
AU - Wallace, Mairi
AU - Samejima, Itaru
AU - Taylor, Martin S
AU - Gordon, Colin
PY - 2003
Y1 - 2003
N2 - Fission yeast Rhp23 and Pus1 represent two families of multiubiquitin chain-binding proteins that associate with the proteasome. We show that both proteins bind to different regions of the proteasome subunit Mts4. The binding site for Pus1 was mapped to a cluster of repetitive sequences also found in the proteasome subunit SpRpn2 and the anaphase-promoting complex/cyclosome (APC/C) subunit Cut4. The putative role of Pus1 as a factor involved in allocation of ubiquitinylated substrates for the proteasome is discussed.
AB - Fission yeast Rhp23 and Pus1 represent two families of multiubiquitin chain-binding proteins that associate with the proteasome. We show that both proteins bind to different regions of the proteasome subunit Mts4. The binding site for Pus1 was mapped to a cluster of repetitive sequences also found in the proteasome subunit SpRpn2 and the anaphase-promoting complex/cyclosome (APC/C) subunit Cut4. The putative role of Pus1 as a factor involved in allocation of ubiquitinylated substrates for the proteasome is discussed.
UR - https://www.scopus.com/pages/publications/0038268188
U2 - 10.1074/jbc.M208281200
DO - 10.1074/jbc.M208281200
M3 - Article
C2 - 12615927
SN - 0021-9258
VL - 278
SP - 16791
EP - 16796
JO - Journal of Biological Chemistry
JF - Journal of Biological Chemistry
IS - 19
ER -