Interfacing non-enzymatic catalysis with living microorganisms

Joanna C. Sadler, Jonathan A. Dennis, Nick W. Johnson, Stephen Wallace

Research output: Contribution to journalReview articlepeer-review

Abstract / Description of output

Interfacing non-enzymatic catalysis with cellular metabolism is emerging as a powerful approach to produce a range of high value small molecules and polymers. In this review, we highlight recent examples from this promising young field. Specifically, we discuss demonstrations of living cells mediating redox processes for biopolymer production, interfacing solar-light driven chemistry with microbial metabolism, and intra- and extracellular non-enzymatic catalysis to generate high value molecules. This review highlights the vast potential of this nascent field to bridge the two disciplines of synthetic chemistry and synthetic biology for a sustainable chemical industry.
Original languageEnglish
Pages (from-to)1073-1083
Number of pages11
JournalRSC Chemical Biology
Issue number4
Early online date4 Jun 2021
Publication statusE-pub ahead of print - 4 Jun 2021


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