@article{19885269962241e2a02d518c646f7700,
title = "Intranasal infection with Chlamydia abortus induces dose-dependent latency and abortion in sheep",
abstract = "Latency is a key feature of the animal pathogen Chlamydia abortus, where infection remains inapparent in the non-pregnant animal and only becomes evident during a subsequent pregnancy. Often the first sign that an animal is infected is abortion occurring late in gestation. Despite this, little is understood of the underlying mechanisms that control latency or the recrudescence of infection that occurs during subsequent pregnancy. The aim of this study was to develop an experimental model of latency by mimicking the natural route of infection through the intranasal inoculation of non-pregnant sheep with C. abortus.",
author = "David Longbottom and Morag Livingstone and Stephen Maley and \{van der Zon\}, Arjan and Mara Rocchi and Kim Wilson and Nicholas Wheelhouse and Mark Dagleish and Kevin Aitchison and Sean Wattegedera and Mintu Nath and Gary Entrican and David Buxton",
note = "Funding: This work was supported by the Scottish Government Rural and Environment Science and Analytical Services Division (http://www.scotland.gov.uk) and by grant number BB/E018939/1 from the Biotechnology and Biological Sciences Research Council (http://www.bbsrc.ac.uk). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.",
year = "2013",
doi = "10.1371/journal.pone.0057950",
language = "English",
volume = "8",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "2",
}