INTRINSIC CURVATURE: A MARKER OF MILLIMETER-SCALE TANGENTIAL CORTICO-CORTICAL CONNECTIVITY?

Lisa Ronan; Rudolph Pienaar; Guy Williams; Ed Bullmore; Tim J. Crow; Neil Roberts; Peter B. Jones; John Suckling; Paul C. Fletcher

doi:10.1142/S0129065711002948

INTRINSIC CURVATURE: A MARKER OF MILLIMETER-SCALE TANGENTIAL CORTICO-CORTICAL CONNECTIVITY?

Lisa Ronan^*, Rudolph Pienaar, Guy Williams, Ed Bullmore, Tim J. Crow, Neil Roberts, Peter B. Jones, John Suckling, Paul C. Fletcher

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

In this paper, we draw a link between cortical intrinsic curvature and the distributions of tangential connection lengths. We suggest that differential rates of surface expansion not only lead to intrinsic curvature of the cortical sheet, but also to differential inter-neuronal spacing. We propose that there follows a consequential change in the profile of neuronal connections: specifically an enhancement of the tendency towards proportionately more short connections. Thus, the degree of cortical intrinsic curvature may have implications for short-range connectivity.

Original language	English
Pages (from-to)	351-366
Number of pages	16
Journal	International Journal of Neural Systems
Volume	21
Issue number	5
DOIs	https://doi.org/10.1142/S0129065711002948
Publication status	Published - Oct 2011

Keywords

cortical connectivity
WHITE-MATTER
SYSTEM
VISUAL-CORTEX
PREFRONTAL CORTEX
SURFACE-BASED ANALYSIS
HUMAN CEREBRAL-CORTEX
NETWORKS
Intrinsic curvature
BRAIN SIZE
COMMUNICATION
SCHIZOPHRENIA
surface morphology

Access to Document

10.1142/S0129065711002948

INTRINSIC CURVATURE A MARKER OF MILLIMETER-SCALE TANGENTIAL CORTICO-CORTICAL CONNECTIVITYAccepted author manuscript, 1.64 MB

http://www.worldscientific.com/doi/abs/10.1142/S0129065711002948

Cite this

@article{05e6c552dd104728b7fa15c82c26321f,

title = "INTRINSIC CURVATURE: A MARKER OF MILLIMETER-SCALE TANGENTIAL CORTICO-CORTICAL CONNECTIVITY?",

abstract = "In this paper, we draw a link between cortical intrinsic curvature and the distributions of tangential connection lengths. We suggest that differential rates of surface expansion not only lead to intrinsic curvature of the cortical sheet, but also to differential inter-neuronal spacing. We propose that there follows a consequential change in the profile of neuronal connections: specifically an enhancement of the tendency towards proportionately more short connections. Thus, the degree of cortical intrinsic curvature may have implications for short-range connectivity.",

keywords = "cortical connectivity, WHITE-MATTER, SYSTEM, VISUAL-CORTEX, PREFRONTAL CORTEX, SURFACE-BASED ANALYSIS, HUMAN CEREBRAL-CORTEX, NETWORKS, Intrinsic curvature, BRAIN SIZE, COMMUNICATION, SCHIZOPHRENIA, surface morphology",

author = "Lisa Ronan and Rudolph Pienaar and Guy Williams and Ed Bullmore and Crow, {Tim J.} and Neil Roberts and Jones, {Peter B.} and John Suckling and Fletcher, {Paul C.}",

year = "2011",

month = oct,

doi = "10.1142/S0129065711002948",

language = "English",

volume = "21",

pages = "351--366",

journal = "International Journal of Neural Systems",

issn = "0129-0657",