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Abstract / Description of output
We have found a negative correlation between evolutionary rate at the protein level (as measured by dN) and intron size in Drosophila. Although such a relation is expected if introns reduce Hill-Robertson interference within genes, it seems more likely to be explained by the higher abundance of cis-regulatory elements in introns (especially first introns) in genes under strong selective constraints.
Original language | English |
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Pages (from-to) | 481-485 |
Journal | Genetics |
Volume | 170 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2005 |
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Dive into the research topics of 'Intron Size and Exon Evolution in Drosophila'. Together they form a unique fingerprint.Projects
- 1 Finished
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New methods for understanding the functional significance of noncoding DNA
Keightley, P. & Charlesworth, B.
1/08/03 → 30/11/07
Project: Research