Iron-catalysed, hydride-mediated reductive cross-coupling of vinyl halides and Grignard reagents

Bryden A. F. Le Bailly, Mark D. Greenhalgh, Stephen P. Thomas

Research output: Contribution to journalArticlepeer-review


An iron-catalysed, hydride-mediated reductive cross-coupling reaction has been developed for the preparation of alkanes. Using a bench-stable iron(II) pre-catalyst, reductive cross-coupling of vinyl iodides, bromides and chlorides with aryl-and alkyl Grignard reagents successfully gave the products of formal sp(3)-sp(3) cross-coupling reactions.

Original languageEnglish
Pages (from-to)1580-1582
Number of pages3
JournalChemical Communications
Issue number10
Publication statusPublished - 2012

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