Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis

Sara J. Weston; Eileen K. Graham; Nicholas A. Turiano; Damaris Aschwanden; Tom Booth; Fleur Harrison; Bryan D James; Nathan A. Lewis; Steve R. Makkar; Swantje Mueller; Kristi M Wisniewski; Tomiko B. Yoneda; Ruixue Zhaoyang; Avron Spiro; Johanna Drewelies; Gert G Wagner; Elisabeth Steinhagen-Thiessen; Ilja Demuth; Sherry Willis; K. Warner Schaie; Martin Sliwinski; Richard Lipton; Mindy J Katz; Ian Deary; Elizabeth M Zelinski; David A Bennett; Perminder S Sachdev; Henry Brodaty; Julian N. Trollor; David Ames; Margaret J Wright; Denis Gerstorf; Mathias Allemand; GM Terrera; Andrea  Piccinin; Scott M.  Hofer; Daniel K. Mroczek

doi:10.1525/collabra.267

Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis

Sara J. Weston, Eileen K. Graham, Nicholas A. Turiano, Damaris Aschwanden, Tom Booth, Fleur Harrison, Bryan D James, Nathan A. Lewis, Steve R. Makkar, Swantje Mueller, Kristi M Wisniewski, Tomiko B. Yoneda, Ruixue Zhaoyang, Avron Spiro, Johanna Drewelies, Gert G Wagner, Elisabeth Steinhagen-Thiessen, Ilja Demuth, Sherry Willis, K. Warner SchaieMartin Sliwinski, Richard Lipton, Mindy J Katz, Ian Deary, Elizabeth M Zelinski, David A Bennett, Perminder S Sachdev, Henry Brodaty, Julian N. Trollor, David Ames, Margaret J Wright, Denis Gerstorf, Mathias Allemand, GM Terrera, Andrea Piccinin, Scott M. Hofer, Daniel K. Mroczek

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Early investigations of the neuroticism by conscientiousness interaction with regards to health have been promising, but to date, there have been no systematic investigations of this interaction that account for the various personality measurement instruments, varying populations, or aspects of health. The current study – the second of three – uses a coordinated analysis approach to test the impact of the neuroticism by conscientiousness interaction on the prevalence and incidence of chronic conditions. Using 15 pre-existing longitudinal studies (N>49,375), we found that conscientiousness did not moderate the relationship between neuroticism and having hypertension (OR=1.00,95%CI[0.98,1.02]), diabetes (OR=1.02[0.99,1.04]), or heart disease (OR=0.99[0.97,1.01]). Similarly, we found that conscientiousness did not moderate the prospective relationship between neuroticism and onset of hypertension (OR=0.98,[0.95,1.01]), diabetes (OR=0.99[0.94,1.05]), or heart disease (OR=0.98[0.94,1.03]). Heterogeneity of effect sizes was largely nonsignificant, with one exception, indicating that the effects are consistent between datasets. Overall, we conclude that there is no evidence that healthy neuroticism, operationalized as the conscientiousness by neuroticism interaction, buffers against chronic conditions.

Original language	English
Journal	Collabra
Early online date	21 Jul 2020
DOIs	https://doi.org/10.1525/collabra.267
Publication status	E-pub ahead of print - 21 Jul 2020

Keywords / Materials (for Non-textual outputs)

healthy neuroticism
conscientiousness
Big Five
IALSA
mortality
coordinated IDA

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10.1525/collabra.267Licence: Creative Commons: Attribution (CC-BY)

TurianoEtalC2020IsHealthyNeuroticismFinal published version, 584 KBLicence: Creative Commons: Attribution (CC-BY)

The Disconnected Mind Phase 3
Cox, S. & Deary, I.
1/04/16 → 31/03/23
Project: Research
RA2662 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2.
Porteous, D.
1/09/13 → 31/08/19
Project: Research

Cite this

Weston, S. J., Graham, E. K., Turiano, N. A., Aschwanden, D., Booth, T., Harrison, F., James, B. D., Lewis, N. A., Makkar, S. R., Mueller, S., Wisniewski, K. M., Yoneda, T. B., Zhaoyang, R., Spiro, A., Drewelies, J., Wagner, G. G., Steinhagen-Thiessen, E., Demuth, I., Willis, S., ... Mroczek, D. K. (2020). Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis. Collabra. Advance online publication. https://doi.org/10.1525/collabra.267

@article{bf73a962420642e89ff931da5f888690,

title = "Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis",

abstract = "Early investigations of the neuroticism by conscientiousness interaction with regards to health have been promising, but to date, there have been no systematic investigations of this interaction that account for the various personality measurement instruments, varying populations, or aspects of health. The current study – the second of three – uses a coordinated analysis approach to test the impact of the neuroticism by conscientiousness interaction on the prevalence and incidence of chronic conditions. Using 15 pre-existing longitudinal studies (N>49,375), we found that conscientiousness did not moderate the relationship between neuroticism and having hypertension (OR=1.00,95%CI[0.98,1.02]), diabetes (OR=1.02[0.99,1.04]), or heart disease (OR=0.99[0.97,1.01]). Similarly, we found that conscientiousness did not moderate the prospective relationship between neuroticism and onset of hypertension (OR=0.98,[0.95,1.01]), diabetes (OR=0.99[0.94,1.05]), or heart disease (OR=0.98[0.94,1.03]). Heterogeneity of effect sizes was largely nonsignificant, with one exception, indicating that the effects are consistent between datasets. Overall, we conclude that there is no evidence that healthy neuroticism, operationalized as the conscientiousness by neuroticism interaction, buffers against chronic conditions.",

keywords = "healthy neuroticism, conscientiousness, Big Five, IALSA, mortality, coordinated IDA",

author = "Weston, {Sara J.} and Graham, {Eileen K.} and Turiano, {Nicholas A.} and Damaris Aschwanden and Tom Booth and Fleur Harrison and James, {Bryan D} and Lewis, {Nathan A.} and Makkar, {Steve R.} and Swantje Mueller and Wisniewski, {Kristi M} and Yoneda, {Tomiko B.} and Ruixue Zhaoyang and Avron Spiro and Johanna Drewelies and Wagner, {Gert G} and Elisabeth Steinhagen-Thiessen and Ilja Demuth and Sherry Willis and Schaie, {K. Warner} and Martin Sliwinski and Richard Lipton and Katz, {Mindy J} and Ian Deary and Zelinski, {Elizabeth M} and Bennett, {David A} and Sachdev, {Perminder S} and Henry Brodaty and Trollor, {Julian N.} and David Ames and Wright, {Margaret J} and Denis Gerstorf and Mathias Allemand and GM Terrera and Andrea Piccinin and Hofer, {Scott M.} and Mroczek, {Daniel K.}",

year = "2020",

month = jul,

day = "21",

doi = "10.1525/collabra.267",

language = "English",

journal = "Collabra",

issn = "2376-6832",

}

Weston, SJ, Graham, EK, Turiano, NA, Aschwanden, D, Booth, T, Harrison, F, James, BD, Lewis, NA, Makkar, SR, Mueller, S, Wisniewski, KM, Yoneda, TB, Zhaoyang, R, Spiro, A, Drewelies, J, Wagner, GG, Steinhagen-Thiessen, E, Demuth, I, Willis, S, Schaie, KW, Sliwinski, M, Lipton, R, Katz, MJ, Deary, I, Zelinski, EM, Bennett, DA, Sachdev, PS, Brodaty, H, Trollor, JN, Ames, D, Wright, MJ, Gerstorf, D, Allemand, M, Terrera, GM, Piccinin, A, Hofer, SM & Mroczek, DK 2020, 'Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis', Collabra. https://doi.org/10.1525/collabra.267

TY - JOUR

T1 - Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis

AU - Weston, Sara J.

AU - Graham, Eileen K.

AU - Turiano, Nicholas A.

AU - Aschwanden, Damaris

AU - Booth, Tom

AU - Harrison, Fleur

AU - James, Bryan D

AU - Lewis, Nathan A.

AU - Makkar, Steve R.

AU - Mueller, Swantje

AU - Wisniewski, Kristi M

AU - Yoneda, Tomiko B.

AU - Zhaoyang, Ruixue

AU - Spiro, Avron

AU - Drewelies, Johanna

AU - Wagner, Gert G

AU - Steinhagen-Thiessen, Elisabeth

AU - Demuth, Ilja

AU - Willis, Sherry

AU - Schaie, K. Warner

AU - Sliwinski, Martin

AU - Lipton, Richard

AU - Katz, Mindy J

AU - Deary, Ian

AU - Zelinski, Elizabeth M

AU - Bennett, David A

AU - Sachdev, Perminder S

AU - Brodaty, Henry

AU - Trollor, Julian N.

AU - Ames, David

AU - Wright, Margaret J

AU - Gerstorf, Denis

AU - Allemand, Mathias

AU - Terrera, GM

AU - Piccinin, Andrea

AU - Hofer, Scott M.

AU - Mroczek, Daniel K.

PY - 2020/7/21

Y1 - 2020/7/21

N2 - Early investigations of the neuroticism by conscientiousness interaction with regards to health have been promising, but to date, there have been no systematic investigations of this interaction that account for the various personality measurement instruments, varying populations, or aspects of health. The current study – the second of three – uses a coordinated analysis approach to test the impact of the neuroticism by conscientiousness interaction on the prevalence and incidence of chronic conditions. Using 15 pre-existing longitudinal studies (N>49,375), we found that conscientiousness did not moderate the relationship between neuroticism and having hypertension (OR=1.00,95%CI[0.98,1.02]), diabetes (OR=1.02[0.99,1.04]), or heart disease (OR=0.99[0.97,1.01]). Similarly, we found that conscientiousness did not moderate the prospective relationship between neuroticism and onset of hypertension (OR=0.98,[0.95,1.01]), diabetes (OR=0.99[0.94,1.05]), or heart disease (OR=0.98[0.94,1.03]). Heterogeneity of effect sizes was largely nonsignificant, with one exception, indicating that the effects are consistent between datasets. Overall, we conclude that there is no evidence that healthy neuroticism, operationalized as the conscientiousness by neuroticism interaction, buffers against chronic conditions.

AB - Early investigations of the neuroticism by conscientiousness interaction with regards to health have been promising, but to date, there have been no systematic investigations of this interaction that account for the various personality measurement instruments, varying populations, or aspects of health. The current study – the second of three – uses a coordinated analysis approach to test the impact of the neuroticism by conscientiousness interaction on the prevalence and incidence of chronic conditions. Using 15 pre-existing longitudinal studies (N>49,375), we found that conscientiousness did not moderate the relationship between neuroticism and having hypertension (OR=1.00,95%CI[0.98,1.02]), diabetes (OR=1.02[0.99,1.04]), or heart disease (OR=0.99[0.97,1.01]). Similarly, we found that conscientiousness did not moderate the prospective relationship between neuroticism and onset of hypertension (OR=0.98,[0.95,1.01]), diabetes (OR=0.99[0.94,1.05]), or heart disease (OR=0.98[0.94,1.03]). Heterogeneity of effect sizes was largely nonsignificant, with one exception, indicating that the effects are consistent between datasets. Overall, we conclude that there is no evidence that healthy neuroticism, operationalized as the conscientiousness by neuroticism interaction, buffers against chronic conditions.

KW - healthy neuroticism

KW - conscientiousness

KW - Big Five

KW - IALSA

KW - mortality

KW - coordinated IDA

U2 - 10.1525/collabra.267

DO - 10.1525/collabra.267

M3 - Article

SN - 2376-6832

JO - Collabra

JF - Collabra

ER -

Is healthy neuroticism associated with chronic conditions? A coordinated integrative data analysis

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Access to Document

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Projects

The Disconnected Mind Phase 3

RA2662 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2.

Cite this