Is there a human homologue to the murine proteolysis-inducing factor?

Barbara M Wieland; Grant D Stewart; Richard J E Skipworth; Kathryn Sangster; Kenneth C H Fearon; James A Ross; Tony J Reiman; Jay Easaw; Marina Mourtzakis; Vishesh Kumar; Brian J Pak; Kathryn Calder; Gerasimos Filippatos; Dimitris T Kremastinos; Monica Palcic; Vickie E Baracos

doi:10.1158/1078-0432.CCR-07-0946

Is there a human homologue to the murine proteolysis-inducing factor?

Barbara M Wieland, Grant D Stewart, Richard J E Skipworth, Kathryn Sangster, Kenneth C H Fearon, James A Ross, Tony J Reiman, Jay Easaw, Marina Mourtzakis, Vishesh Kumar, Brian J Pak, Kathryn Calder, Gerasimos Filippatos, Dimitris T Kremastinos, Monica Palcic, Vickie E Baracos

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

A tumor-derived proteolysis-inducing factor (PIF) is suggested to be a potent catabolic factor in skeletal muscle of mice and humans. We aimed to establish the clinical significance of PIF in cancer patients and to elucidate its structural features.

Original language	English
Pages (from-to)	4984-92
Number of pages	9
Journal	Clinical Cancer Research
Volume	13
Issue number	17
DOIs	https://doi.org/10.1158/1078-0432.CCR-07-0946
Publication status	Published - 2007

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10.1158/1078-0432.CCR-07-0946

Cite this

Wieland, B. M., Stewart, G. D., Skipworth, R. J. E., Sangster, K., Fearon, K. C. H., Ross, J. A., Reiman, T. J., Easaw, J., Mourtzakis, M., Kumar, V., Pak, B. J., Calder, K., Filippatos, G., Kremastinos, D. T., Palcic, M., & Baracos, V. E. (2007). Is there a human homologue to the murine proteolysis-inducing factor? Clinical Cancer Research, 13(17), 4984-92. https://doi.org/10.1158/1078-0432.CCR-07-0946

@article{d22b92842d8d4134b7d73618c07ffef6,

title = "Is there a human homologue to the murine proteolysis-inducing factor?",

abstract = "A tumor-derived proteolysis-inducing factor (PIF) is suggested to be a potent catabolic factor in skeletal muscle of mice and humans. We aimed to establish the clinical significance of PIF in cancer patients and to elucidate its structural features.",

author = "Wieland, {Barbara M} and Stewart, {Grant D} and Skipworth, {Richard J E} and Kathryn Sangster and Fearon, {Kenneth C H} and Ross, {James A} and Reiman, {Tony J} and Jay Easaw and Marina Mourtzakis and Vishesh Kumar and Pak, {Brian J} and Kathryn Calder and Gerasimos Filippatos and Kremastinos, {Dimitris T} and Monica Palcic and Baracos, {Vickie E}",

year = "2007",

doi = "10.1158/1078-0432.CCR-07-0946",

language = "English",

volume = "13",

pages = "4984--92",

journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research Inc.",