Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia

M Dungerwalla; N Osuji; A D Waldman; F Al Jehani; A Mehta; R Taylor; A Wotherspoon; G Cogill; E Matutes

doi:10.1111/j.1365-2141.2005.05629.x

Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia

M Dungerwalla, N Osuji, A D Waldman, F Al Jehani, A Mehta, R Taylor, A Wotherspoon, G Cogill, E Matutes

Research output: Contribution to journal › Article › peer-review

Abstract

Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.

Original language	English
Pages (from-to)	511-5
Number of pages	5
Journal	British journal of haematology
Volume	130
Issue number	4
DOIs	https://doi.org/10.1111/j.1365-2141.2005.05629.x
Publication status	Published - Aug 2005

Keywords

Adult
Antiviral Agents
Brain Neoplasms
Disease Progression
Frontal Lobe
Humans
Interferons
Leukemia-Lymphoma, Adult T-Cell
Magnetic Resonance Imaging
Male
Palliative Care
Tomography, X-Ray Computed
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Review

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title = "Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia",

abstract = "Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.",

keywords = "Adult, Antiviral Agents, Brain Neoplasms, Disease Progression, Frontal Lobe, Humans, Interferons, Leukemia-Lymphoma, Adult T-Cell, Magnetic Resonance Imaging, Male, Palliative Care, Tomography, X-Ray Computed, Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review",

author = "M Dungerwalla and N Osuji and Waldman, {A D} and {Al Jehani}, F and A Mehta and R Taylor and A Wotherspoon and G Cogill and E Matutes",

year = "2005",

month = aug,

doi = "10.1111/j.1365-2141.2005.05629.x",

language = "English",

volume = "130",

pages = "511--5",

journal = "British journal of haematology",

issn = "0007-1048",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia

AU - Dungerwalla, M

AU - Osuji, N

AU - Waldman, A D

AU - Al Jehani, F

AU - Mehta, A

AU - Taylor, R

AU - Wotherspoon, A

AU - Cogill, G

AU - Matutes, E

PY - 2005/8

Y1 - 2005/8

N2 - Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.

AB - Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.

KW - Adult

KW - Antiviral Agents

KW - Brain Neoplasms

KW - Disease Progression

KW - Frontal Lobe

KW - Humans

KW - Interferons

KW - Leukemia-Lymphoma, Adult T-Cell

KW - Magnetic Resonance Imaging

KW - Male

KW - Palliative Care

KW - Tomography, X-Ray Computed

KW - Case Reports

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1111/j.1365-2141.2005.05629.x

DO - 10.1111/j.1365-2141.2005.05629.x

M3 - Article

C2 - 16098064

VL - 130

SP - 511

EP - 515

JO - British journal of haematology

JF - British journal of haematology

SN - 0007-1048

IS - 4

ER -