Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes

C. Auffray, J.W. Lillie, D. Arnot

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

DNA sequences of four human class II histocompatibility antigen α chain DNA sequences (derived from cDNA and genomic clones representing DC1α, DC4α, DXα and SBα) are presented and compared to DRα and to mouse I-Aα and I-Eα sequences. These data suggest possible mechanisms for the generation of polymorphism and the evolution of the DR, DC and SB families.
Original languageEnglish
Pages (from-to)327-333
Number of pages7
JournalNature
Volume308
Issue number5957
Publication statusPublished - 1 Jan 1984

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