Abstract
DNA sequences of four human class II histocompatibility antigen α chain DNA sequences (derived from cDNA and genomic clones representing DC1α, DC4α, DXα and SBα) are presented and compared to DRα and to mouse I-Aα and I-Eα sequences. These data suggest possible mechanisms for the generation of polymorphism and the evolution of the DR, DC and SB families.
Original language | English |
---|---|
Pages (from-to) | 327-333 |
Number of pages | 7 |
Journal | Nature |
Volume | 308 |
Issue number | 5957 |
Publication status | Published - 1 Jan 1984 |