'Ivory wave' toxicity in recreational drug users; integration of clinical and poisons information services to manage legal high poisoning

Douglas B Murray; Stephen Potts; Carole Haxton; Gillian Jackson; Euan A Sandilands; John Ramsey; Malgorzata Puchnarewicz; David W Holt; Atholl Johnston; D Nicholas Bateman; James W Dear

doi:10.3109/15563650.2011.647992

'Ivory wave' toxicity in recreational drug users; integration of clinical and poisons information services to manage legal high poisoning

Douglas B Murray, Stephen Potts, Carole Haxton, Gillian Jackson, Euan A Sandilands, John Ramsey, Malgorzata Puchnarewicz, David W Holt, Atholl Johnston, D Nicholas Bateman, James W Dear

Research output: Contribution to journal › Article › peer-review

Abstract

Novel psychoactive substances or 'legal highs' can be defined as psychoactive substances that have been developed to avoid existing drug control measures. Consistency of name, but with change in the content of the product, may cause harm. This could result in clusters of users being poisoned and developing unexpected physical and psychiatric symptoms. We describe such an event and the clinical phenotypes of a cluster of patients poisoned with a novel psychoactive substance in 'ivory wave' and analyze data from the National Poisons Information Service (NPIS) to estimate use across the United Kingdom. In addition, the likely active ingredient in this cluster of 'ivory wave' poisonings was identified.

Original language	English
Pages (from-to)	108-13
Number of pages	6
Journal	Clinical Toxicology
Volume	50
Issue number	2
DOIs	https://doi.org/10.3109/15563650.2011.647992
Publication status	Published - 2012

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Murray, D. B., Potts, S., Haxton, C., Jackson, G., Sandilands, E. A., Ramsey, J., Puchnarewicz, M., Holt, D. W., Johnston, A., Nicholas Bateman, D., & Dear, J. W. (2012). 'Ivory wave' toxicity in recreational drug users; integration of clinical and poisons information services to manage legal high poisoning. Clinical Toxicology, 50(2), 108-13. https://doi.org/10.3109/15563650.2011.647992

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abstract = "Novel psychoactive substances or 'legal highs' can be defined as psychoactive substances that have been developed to avoid existing drug control measures. Consistency of name, but with change in the content of the product, may cause harm. This could result in clusters of users being poisoned and developing unexpected physical and psychiatric symptoms. We describe such an event and the clinical phenotypes of a cluster of patients poisoned with a novel psychoactive substance in 'ivory wave' and analyze data from the National Poisons Information Service (NPIS) to estimate use across the United Kingdom. In addition, the likely active ingredient in this cluster of 'ivory wave' poisonings was identified.",

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Murray, DB, Potts, S, Haxton, C, Jackson, G, Sandilands, EA, Ramsey, J, Puchnarewicz, M, Holt, DW, Johnston, A, Nicholas Bateman, D & Dear, JW 2012, ''Ivory wave' toxicity in recreational drug users; integration of clinical and poisons information services to manage legal high poisoning', Clinical Toxicology, vol. 50, no. 2, pp. 108-13. https://doi.org/10.3109/15563650.2011.647992

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AU - Murray, Douglas B

AU - Potts, Stephen

AU - Haxton, Carole

AU - Jackson, Gillian

AU - Sandilands, Euan A

AU - Ramsey, John

AU - Puchnarewicz, Malgorzata

AU - Holt, David W

AU - Johnston, Atholl

AU - Nicholas Bateman, D

AU - Dear, James W

PY - 2012

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AB - Novel psychoactive substances or 'legal highs' can be defined as psychoactive substances that have been developed to avoid existing drug control measures. Consistency of name, but with change in the content of the product, may cause harm. This could result in clusters of users being poisoned and developing unexpected physical and psychiatric symptoms. We describe such an event and the clinical phenotypes of a cluster of patients poisoned with a novel psychoactive substance in 'ivory wave' and analyze data from the National Poisons Information Service (NPIS) to estimate use across the United Kingdom. In addition, the likely active ingredient in this cluster of 'ivory wave' poisonings was identified.

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'Ivory wave' toxicity in recreational drug users; integration of clinical and poisons information services to manage legal high poisoning

Abstract

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