Keeping a lid on shoot regeneration: SIZ1 suppresses wound-induced developmental reprogramming

Research output: Contribution to journalArticlepeer-review


Plants have the remarkable ability to regenerate tissues and organs in response to wounding. This process relies on the formation of callus, a mass of unorganized cells that provides protection to the wounding site while allowing cell reprogramming and proliferation. Callus can be formed in vitro by incubating explants on auxin-rich callus-inducing medium (CIM), which stimulates reactivation of lateral root formation (Sugimoto et al., 2010). Subsequently, callus can be transferred to cytokinin-rich shoot-inducing medium (SIM), which triggers reprogramming of callus cells to shoot meristem identity and allows regeneration of a whole plant. Extensive transcriptional networks involving a wide range of transcription factors, hormones, and additional regulators have been identified that control each step of these developmental transitions. However, it has remained unknown if posttranslational regulation occurs during these wounding and developmental processes.
Original languageEnglish
Pages (from-to)10-11
JournalPlant physiology
Issue number1
Publication statusPublished - 4 Sep 2020


Dive into the research topics of 'Keeping a lid on shoot regeneration: SIZ1 suppresses wound-induced developmental reprogramming'. Together they form a unique fingerprint.

Cite this