KRABs RegulaTE Gene Expression beyond the Embryo.

Christopher J Playfoot; Ian Adams

doi:10.1016/j.devcel.2016.03.006

KRABs RegulaTE Gene Expression beyond the Embryo.

Christopher J Playfoot, Ian Adams

Research output: Contribution to journal › Comment/debate

Abstract

Transposable element (TE) silencing is initiated early in mammalian development and maintained during somatic differentiation. Reporting in this issue of Developmental Cell, Ecco et al. (2016) show that in somatic tissues, TE regulation, and its subsequent effect on host gene transcription, is dynamic rather than locked in a silent state.

Original language	English
Pages (from-to)	591-592
Journal	Developmental Cell
Volume	36
Issue number	6
DOIs	https://doi.org/10.1016/j.devcel.2016.03.006
Publication status	Published - 21 Mar 2016

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title = "KRABs RegulaTE Gene Expression beyond the Embryo.",

abstract = "Transposable element (TE) silencing is initiated early in mammalian development and maintained during somatic differentiation. Reporting in this issue of Developmental Cell, Ecco et al. (2016) show that in somatic tissues, TE regulation, and its subsequent effect on host gene transcription, is dynamic rather than locked in a silent state.",

author = "Playfoot, {Christopher J} and Ian Adams",

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AU - Playfoot, Christopher J

AU - Adams, Ian

PY - 2016/3/21

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N2 - Transposable element (TE) silencing is initiated early in mammalian development and maintained during somatic differentiation. Reporting in this issue of Developmental Cell, Ecco et al. (2016) show that in somatic tissues, TE regulation, and its subsequent effect on host gene transcription, is dynamic rather than locked in a silent state.

AB - Transposable element (TE) silencing is initiated early in mammalian development and maintained during somatic differentiation. Reporting in this issue of Developmental Cell, Ecco et al. (2016) show that in somatic tissues, TE regulation, and its subsequent effect on host gene transcription, is dynamic rather than locked in a silent state.

U2 - 10.1016/j.devcel.2016.03.006

DO - 10.1016/j.devcel.2016.03.006

M3 - Comment/debate

VL - 36

SP - 591

EP - 592

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 6

ER -

KRABs RegulaTE Gene Expression beyond the Embryo.

Abstract

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