Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

K R Bales, T Verina, R C Dodel, Y Du, L Altstiel, M Bender, P Hyslop, E M Johnstone, S P Little, D J Cummins, P Piccardo, B Ghetti, S M Paul

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)263-4
Number of pages2
JournalNature Genetics
Issue number3
Publication statusPublished - Nov 1997
Externally publishedYes


  • Age Factors
  • Alzheimer Disease
  • Amyloid beta-Peptides
  • Amyloid beta-Protein Precursor
  • Animals
  • Apolipoproteins E
  • Brain
  • Humans
  • Immunohistochemistry
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred DBA
  • Mice, Knockout
  • Mice, Transgenic
  • Polymerase Chain Reaction
  • RNA, Messenger

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