Abstract / Description of output
Phylogenetic inference is an intractable statistical problem on a complex space. Markov chain Monte Carlo methods are the primary tool for Bayesian phylogenetic inference, but it is challenging to construct efficient schemes to explore the associated posterior distribution or assess their performance. Existing approaches are unable to diagnose mixing or convergence of Markov schemes jointly across all components of a phylogenetic model. Lagged couplings of Markov chain Monte Carlo algorithms have recently been developed on simpler spaces to diagnose convergence and construct unbiased estimators. We describe a contractive coupling of Markov chains targeting a posterior distribution over a space of phylogenetic trees with branch lengths, scalar parameters and latent variables. We use these couplings to assess mixing and convergence of Markov chains jointly across all components of the phylogenetic model on trees with up to 200 leaves. Samples from our coupled chains may also be used to construct unbiased estimators.
Original language | English |
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Pages (from-to) | 1419-1443 |
Number of pages | 25 |
Journal | Annals of Applied Statistics |
Volume | 17 |
Issue number | 2 |
Early online date | 1 May 2023 |
DOIs | |
Publication status | Published - 30 Jun 2023 |
Keywords / Materials (for Non-textual outputs)
- Bayesian phylogenetic inference
- couplings
- Markov chain Monte Carlo methods