Layout of transcallosal activity in cat visual cortex revealed by optical imaging

N. L. Rochefort*, P. Buzas, Z. F. Kisvarday, U. T. Eysel, C. Milleret

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The contribution of interhemispheric connections to functional maps in cat visual cortex was investigated by using optical imaging of intrinsic signals. In order to isolate the functional inputs arriving via the corpus callosum (CC) from other inputs, we used the split-chiasm preparation. The regions activated through the CC in visual areas 17 (A17) and 18 (A18) were localized and characterized by stimulating monocularly split-chiasm cats with moving, high contrast oriented gratings. We found that the CC mediates the activation of orientation selective domains in the transition zone (TZ) between A17 and A18 and occasionally within portions of both of these areas. We observed transcallosally activated orientation domains all along the TZ without any obvious interruption, and these domains were arranged around "pinwheel" centers. Interestingly, the TZ was divided in two parallel regions, which resemble A17 and A18 in their preferred temporal and spatial frequencies. Finally, we demonstrated that orientation maps evoked through the transcallosal and geniculo-cortical pathways were similar within the TZ, indicating a convergence of inputs of matching orientations in this region. These results contribute to a better understanding of the role of the CC in visual perception of orientations and shapes, at the level of the visual cortex. (c) 2007 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)804-821
Number of pages18
JournalNeuroImage
Volume36
Issue number3
DOIs
Publication statusPublished - 1 Jul 2007

Keywords

  • corpus callosum
  • callosal connections
  • interhemispheric
  • long-range connections
  • A17
  • A18
  • ORIENTATION PREFERENCE MAPS
  • SHREW STRIATE CORTEX
  • CALLOSAL CONNECTIONS
  • CORPUS-CALLOSUM
  • INTERHEMISPHERIC CONNECTIONS
  • HORIZONTAL CONNECTIONS
  • OCULAR DOMINANCE
  • RETINOTOPIC ORGANIZATION
  • TOPOGRAPHIC ORGANIZATION
  • FUNCTIONAL-ORGANIZATION

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