Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study

Anna Giulia Pavon; Pier Giorgio Masci; Lorenzo Pucci; Antonio Landi; Amit Bermano; Amir Vaxman; Craig Gotsman; Tobias Rutz; Pierre Monney; Rita Godihno; David Saraiva Rodrigues; Olivier Muller; Marco Valgimigli; Juerg Schwitter

doi:10.1007/s10554-022-02536-9

Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study

Anna Giulia Pavon, Pier Giorgio Masci, Lorenzo Pucci, Antonio Landi, Amit Bermano, Amir Vaxman, Craig Gotsman, Tobias Rutz, Pierre Monney, Rita Godihno, David Saraiva Rodrigues, Olivier Muller, Marco Valgimigli, Juerg Schwitter

Research output: Contribution to journal › Article › peer-review

Abstract

Left atrium (LA) plays a key role in the overall cardiac performance. However, it remains unclear how LA adapts, in terms of function and volumes, to left ventricular dysfunction in the acute and post-acute phases of myocardial infarction. LA volumes and function were evaluated in patients in the acute phase of ST-segment elevation myocardial infarction (acute-STEMI group) and in the post-acute phase after STEMI (post-acute STEMI group). Ten age and sex-matched healthy controls served as control group. In all subjects LA was assessed by a compressed-sensing cine pulse sequence and by a 3D non-model-based reconstruction. LV infarct size and microvascular obstruction were determined on late-gadolinium-enhancement data and LV myocardial oedema and myocardial haemorrhage were measured on T2-mapping data. Indexed LA maximum and minimum volumes did not differ between the acute (n = 50) and post-acute (n = 47) STEMI groups. LA active emptying fraction (LAAEF) was higher in the acute-STEMI as compared with the post-acute STEMI groups (0.63 ± 0.23 vs 0.37 ± 0.24, p

Original language	English
Pages (from-to)	1533-1543
Number of pages	11
Journal	The International Journal of Cardiovascular Imaging
Volume	38
Issue number	7
Early online date	17 Feb 2022
DOIs	https://doi.org/10.1007/s10554-022-02536-9
Publication status	Published - 1 Jul 2022

Keywords / Materials (for Non-textual outputs)

ST-segment elevation myocardial infarction
Cardiovascular magnetic resonance
Left atrium
Left atrium function

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Pavon, A. G., Masci, P. G., Pucci, L., Landi, A., Bermano, A., Vaxman, A., Gotsman, C., Rutz, T., Monney, P., Godihno, R., Saraiva Rodrigues, D., Muller, O., Valgimigli, M., & Schwitter, J. (2022). Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study. The International Journal of Cardiovascular Imaging, 38(7), 1533-1543. https://doi.org/10.1007/s10554-022-02536-9

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title = "Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study",

abstract = "Left atrium (LA) plays a key role in the overall cardiac performance. However, it remains unclear how LA adapts, in terms of function and volumes, to left ventricular dysfunction in the acute and post-acute phases of myocardial infarction. LA volumes and function were evaluated in patients in the acute phase of ST-segment elevation myocardial infarction (acute-STEMI group) and in the post-acute phase after STEMI (post-acute STEMI group). Ten age and sex-matched healthy controls served as control group. In all subjects LA was assessed by a compressed-sensing cine pulse sequence and by a 3D non-model-based reconstruction. LV infarct size and microvascular obstruction were determined on late-gadolinium-enhancement data and LV myocardial oedema and myocardial haemorrhage were measured on T2-mapping data. Indexed LA maximum and minimum volumes did not differ between the acute (n = 50) and post-acute (n = 47) STEMI groups. LA active emptying fraction (LAAEF) was higher in the acute-STEMI as compared with the post-acute STEMI groups (0.63 ± 0.23 vs 0.37 ± 0.24, p ",

keywords = "ST-segment elevation myocardial infarction, Cardiovascular magnetic resonance, Left atrium, Left atrium function",

author = "Pavon, {Anna Giulia} and Masci, {Pier Giorgio} and Lorenzo Pucci and Antonio Landi and Amit Bermano and Amir Vaxman and Craig Gotsman and Tobias Rutz and Pierre Monney and Rita Godihno and {Saraiva Rodrigues}, David and Olivier Muller and Marco Valgimigli and Juerg Schwitter",

note = "Funding Information: The study was supported by Swiss Heart Foundation (Grant to J. Schwitter, MD). Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Nature B.V.",

year = "2022",

month = jul,

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doi = "10.1007/s10554-022-02536-9",

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Pavon, AG, Masci, PG, Pucci, L, Landi, A, Bermano, A, Vaxman, A, Gotsman, C, Rutz, T, Monney, P, Godihno, R, Saraiva Rodrigues, D, Muller, O, Valgimigli, M & Schwitter, J 2022, 'Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study', The International Journal of Cardiovascular Imaging, vol. 38, no. 7, pp. 1533-1543. https://doi.org/10.1007/s10554-022-02536-9

TY - JOUR

T1 - Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study

AU - Pavon, Anna Giulia

AU - Masci, Pier Giorgio

AU - Pucci, Lorenzo

AU - Landi, Antonio

AU - Bermano, Amit

AU - Vaxman, Amir

AU - Gotsman, Craig

AU - Rutz, Tobias

AU - Monney, Pierre

AU - Godihno, Rita

AU - Saraiva Rodrigues, David

AU - Muller, Olivier

AU - Valgimigli, Marco

AU - Schwitter, Juerg

PY - 2022/7/1

Y1 - 2022/7/1

N2 - Left atrium (LA) plays a key role in the overall cardiac performance. However, it remains unclear how LA adapts, in terms of function and volumes, to left ventricular dysfunction in the acute and post-acute phases of myocardial infarction. LA volumes and function were evaluated in patients in the acute phase of ST-segment elevation myocardial infarction (acute-STEMI group) and in the post-acute phase after STEMI (post-acute STEMI group). Ten age and sex-matched healthy controls served as control group. In all subjects LA was assessed by a compressed-sensing cine pulse sequence and by a 3D non-model-based reconstruction. LV infarct size and microvascular obstruction were determined on late-gadolinium-enhancement data and LV myocardial oedema and myocardial haemorrhage were measured on T2-mapping data. Indexed LA maximum and minimum volumes did not differ between the acute (n = 50) and post-acute (n = 47) STEMI groups. LA active emptying fraction (LAAEF) was higher in the acute-STEMI as compared with the post-acute STEMI groups (0.63 ± 0.23 vs 0.37 ± 0.24, p

AB - Left atrium (LA) plays a key role in the overall cardiac performance. However, it remains unclear how LA adapts, in terms of function and volumes, to left ventricular dysfunction in the acute and post-acute phases of myocardial infarction. LA volumes and function were evaluated in patients in the acute phase of ST-segment elevation myocardial infarction (acute-STEMI group) and in the post-acute phase after STEMI (post-acute STEMI group). Ten age and sex-matched healthy controls served as control group. In all subjects LA was assessed by a compressed-sensing cine pulse sequence and by a 3D non-model-based reconstruction. LV infarct size and microvascular obstruction were determined on late-gadolinium-enhancement data and LV myocardial oedema and myocardial haemorrhage were measured on T2-mapping data. Indexed LA maximum and minimum volumes did not differ between the acute (n = 50) and post-acute (n = 47) STEMI groups. LA active emptying fraction (LAAEF) was higher in the acute-STEMI as compared with the post-acute STEMI groups (0.63 ± 0.23 vs 0.37 ± 0.24, p

KW - ST-segment elevation myocardial infarction

KW - Cardiovascular magnetic resonance

KW - Left atrium

KW - Left atrium function

U2 - 10.1007/s10554-022-02536-9

DO - 10.1007/s10554-022-02536-9

M3 - Article

SN - 1573-0743

VL - 38

SP - 1533

EP - 1543

JO - The International Journal of Cardiovascular Imaging

JF - The International Journal of Cardiovascular Imaging

IS - 7

ER -

Left atrial adaptation in ischemic heart disease: insights from a cardiovascular magnetic resonance study

Abstract

Keywords / Materials (for Non-textual outputs)

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