OBJECTIVES: The objectives of this review are to investigate the effectiveness of lifestyle interventions for type 2 diabetes prevention in children and adolescents of African descent in the Organization for Economic Co-operation and Development (OECD) member countries and to attempt to ascertain what aspects of these interventions are most effective in this population.
INTRODUCTION: Lifestyle interventions have been shown to prevent or delay the onset of type 2 diabetes; however, the extent to which these interventions are effective for children and adolescents of African descent is not well established. The increasing type 2 diabetes incidence and prevalence in children and adolescents of African descent in some OECD member countries underscores the need to pool available evidence to ascertain the effectiveness of lifestyle interventions for type 2 diabetes prevention in this population.
INCLUSION CRITERIA: Lifestyle interventions to be considered include individual- or group-based lifestyle or behavioral modification interventions aimed at preventing or delaying the onset of type 2 diabetes in children and adolescents of African descent aged 19 years and under in OECD countries. Randomized controlled trials and non-randomized studies that assess the effectiveness of lifestyle interventions for type 2 diabetes prevention will be considered.
METHODS: The databases to be searched include MEDLINE (Ovid), Embase (Elsevier), CINAHL (EBSCO), PsycINFO (EBSCO), Social Services Abstracts, Cochrane Central Register of Controlled Trials (CENTRAL; Wiley), and ProQuest Dissertations and Theses Global databases. Two independent reviewers will conduct the titles, abstracts, and full-text screening, then followed by critical appraisal and data extraction. Data will undergo meta-analysis where appropriate, and otherwise narrative synthesis.
SYSTEMATIC REVIEW REGISTRATION NUMBER: PROSPERO registration number CRD42021247267.