Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice

Larissa Fabritz, Mark G Hoogendijk, Brendon P Scicluna, Shirley C M van Amersfoorth, Lisa Fortmueller, Susanne Wolf, Sandra Laakmann, Nina Kreienkamp, Ilaria Piccini, Günter Breithardt, Patricia Ruiz Noppinger, Henning Witt, Klaus Ebnet, Thomas Wichter, Bodo Levkau, Werner W Franke, Sebastian Pieperhoff, Jacques M T de Bakker, Ruben Coronel, Paulus Kirchhof

Research output: Contribution to journalArticlepeer-review

Abstract

We used a murine model of arrhythmogenic right ventricular cardiomyopathy (ARVC) to test whether reducing ventricular load prevents or slows development of this cardiomyopathy.
Original languageEnglish
Pages (from-to)740-50
Number of pages11
JournalJournal of the American College of Cardiology
Volume57
Issue number6
DOIs
Publication statusPublished - 2011

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