Local lung responses following local lung challenge with recombinant lungworm antigen in systemically sensitized sheep

D D Collie; C N MacAldowie; A D Pemberton; C J Woodall; N McLean; C Hodgson; M W Kennedy; H R Miller

Local lung responses following local lung challenge with recombinant lungworm antigen in systemically sensitized sheep

D D Collie, C N MacAldowie, A D Pemberton, C J Woodall, N McLean, C Hodgson, M W Kennedy, H R Miller

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic mast cell-mediated inflammation may contribute significantly towards the extensive tissue remodelling that is a feature of lungworm infection in ruminants. Understanding the factors that control tissue remodelling is a necessary step toward effective management and treatment of conditions that feature such pathology.

Original language	English
Pages (from-to)	1636-47
Number of pages	12
Journal	Clinical & Experimental Allergy
Volume	31
Issue number	10
Publication status	Published - Oct 2001

Keywords / Materials (for Non-textual outputs)

Models, Animal
Animals
Cell Count
Recombinant Proteins
Dictyocaulus
Sheep
Bronchial Provocation Tests
Serine Endopeptidases
Immunization
Leukocyte Count
Chymases
Neutrophils
Lung
Eosinophils
Bronchoalveolar Lavage Fluid
Immunoglobulin G
Transforming Growth Factor beta
Mast Cells
Immunohistochemistry
Male
Female
Antigens, Helminth

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Local lung responses following local lung challenge with recombinant lungworm antigen in systemically sensitized sheepAccepted author manuscript, 186 KB

STEM CELL IN PULMONARY DIS
Collie, D. (Principal Investigator)
UK-based charities
1/10/97 → 30/09/01
Project: Research

Cite this

@article{81a2268d33ec4d299bb05a790ef4105a,

title = "Local lung responses following local lung challenge with recombinant lungworm antigen in systemically sensitized sheep",

abstract = "Chronic mast cell-mediated inflammation may contribute significantly towards the extensive tissue remodelling that is a feature of lungworm infection in ruminants. Understanding the factors that control tissue remodelling is a necessary step toward effective management and treatment of conditions that feature such pathology.",

keywords = "Models, Animal, Animals, Cell Count, Recombinant Proteins, Dictyocaulus, Sheep, Bronchial Provocation Tests, Serine Endopeptidases, Immunization, Leukocyte Count, Chymases, Neutrophils, Lung, Eosinophils, Bronchoalveolar Lavage Fluid, Immunoglobulin G, Transforming Growth Factor beta, Mast Cells, Immunohistochemistry, Male, Female, Antigens, Helminth",

author = "Collie, {D D} and MacAldowie, {C N} and Pemberton, {A D} and Woodall, {C J} and N McLean and C Hodgson and Kennedy, {M W} and Miller, {H R}",

year = "2001",

month = oct,

language = "English",

volume = "31",

pages = "1636--47",

journal = "Clinical & Experimental Allergy",

issn = "0954-7894",

publisher = "Wiley-Blackwell",

number = "10",

}

TY - JOUR

T1 - Local lung responses following local lung challenge with recombinant lungworm antigen in systemically sensitized sheep

AU - Collie, D D

AU - MacAldowie, C N

AU - Pemberton, A D

AU - Woodall, C J

AU - McLean, N

AU - Hodgson, C

AU - Kennedy, M W

AU - Miller, H R

PY - 2001/10

Y1 - 2001/10

N2 - Chronic mast cell-mediated inflammation may contribute significantly towards the extensive tissue remodelling that is a feature of lungworm infection in ruminants. Understanding the factors that control tissue remodelling is a necessary step toward effective management and treatment of conditions that feature such pathology.

AB - Chronic mast cell-mediated inflammation may contribute significantly towards the extensive tissue remodelling that is a feature of lungworm infection in ruminants. Understanding the factors that control tissue remodelling is a necessary step toward effective management and treatment of conditions that feature such pathology.

KW - Models, Animal

KW - Animals

KW - Cell Count

KW - Recombinant Proteins

KW - Dictyocaulus

KW - Sheep

KW - Bronchial Provocation Tests

KW - Serine Endopeptidases

KW - Immunization

KW - Leukocyte Count

KW - Chymases

KW - Neutrophils

KW - Lung

KW - Eosinophils

KW - Bronchoalveolar Lavage Fluid

KW - Immunoglobulin G

KW - Transforming Growth Factor beta

KW - Mast Cells

KW - Immunohistochemistry

KW - Male

KW - Female

KW - Antigens, Helminth

M3 - Article

C2 - 11678866

SN - 0954-7894

VL - 31

SP - 1636

EP - 1647

JO - Clinical & Experimental Allergy

JF - Clinical & Experimental Allergy

IS - 10

ER -

Local lung responses following local lung challenge with recombinant lungworm antigen in systemically sensitized sheep

Abstract

Keywords / Materials (for Non-textual outputs)

Access to Document

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Projects

STEM CELL IN PULMONARY DIS

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