Looking into the barrel of the RNA exosome

Claudia Schneider, David Tollervey

Research output: Contribution to journalComment/debatepeer-review


The exosome complex has key roles in RNA processing and quality control. Single-particle EM analyses now provide compelling evidence for two distinct pathways by which substrate RNAs can pass through the exosome structure to reach the catalytic site for exonuclease digestion.
Original languageEnglish
Pages (from-to)17-18
Number of pages2
JournalNature Structural and Molecular Biology
Issue number1
Publication statusPublished - 6 Jan 2014


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